High rate of muscle injury despite no changes in physical, physiological and psychophysiological parameters in a professional football team during a long-congested fixture period.

This study aimed to analyse match availability, participation, and muscle injury incidence and to compare the effect of time intervals between matches (3-4 versus 6-7 days) on physical, physiological, and psychophysiological parameters in a professional football team during a prolonged congested fixture period. Thirteen professional male football players (29.2 ± 4.8 years old; 78.5 ± 8.3 kg; 179.3 ± 8.8 cm;) participated. Data were collected during 17 consecutive weeks for 35 official matches separated by an average interval of ≤ 3.5 days. Results showed a player availability of 84.8 ± 16.1% while match participation was 68.8% ± 6.4%. Muscle injury incidence was 19.0/ 1,000 hours of match exposure. These injuries occurred after individual players participated in sequences of 8.3 ± 3.3 consecutive matches with intervals of 3.8 ± 0.8 days. No differences were observed in physical performance or in fatigue-related parameters irrespective of the time interval between matches. A high player availability rate was observed. No differences were observed in physical, physiological, and psychophysiological indices of performance when comparing shorter and longer time intervals between consecutive matches.Prolonged exposure to fixture congestion resulted in an high risk of incurring muscle injury.

Intra-seasonal variation of injury patterns among German Bundesliga soccer players.

OBJECTIVE: High fluctuations in injury-risk during the playing season in soccer have been reported. As seasons are structured in periods with homogenous loads and intensities, we investigated injury-risk over season periods, contrarily to previous studies adopting a month-based approach. DESIGN: Cohort study; Level of evidence, 2. METHODS: Incidence-rate ratios (IRRs) for match and training injuries were compared across six consecutive seasons of German Bundesliga, divided into six periods each: Pre-season (PS), winter-break (WB), quarter 1-4: (Q1-Q4). RESULTS: Significant variations in injury-risk were observed for match and training injuries. IRRs in matches was 1.30 (95% CI: 1.11-1.53) times higher in Q3 and 1.53 (95% CI: 1.31-1.78) higher in Q4 compared to Q1. For training injuries, IRR peaked in Q1 and Q3 followed by a marked decrease in each subsequent quarter. Compared to Q4, IRR was 1.62 (95% CI: 1.40-1.86) times higher during Q3 and 1.78 (95% CI: 1.53-2.07) times higher in Q1. IRR was significantly higher in the competitive season compared to pre-season across match (IRR: 2.00, 95% CI: 1.30-3.00) and training (IRR: 1.27, 95% CI: 1.11-1.43) injuries. CONCLUSIONS: The increased match IRRs later during the season indicate that, in practice, coaches should consider putting even more emphasis on recovery in the last part of the season. Moreover, training injuries seem to indicate a carry-over effect. Further studies need to investigate how training during preparatory phases can be implemented in a way that prevents injuries during the competitive season.

Detection of major histocompatibility complex molecules in processed allogeneic bone blocks for use in alveolar ridge reconstruction.

OBJECTIVES: Because processed allogenic bone blocks contain remnants of cells and other organic material, the present study examined the putative presence of major histocompatibility complex (MHC) molecules in protein extracts derived from processed allogeneic bone blocks. STUDY DESIGN: Protein content and the immunogenic potential of 3 different processed allografts (Osteograft, DIZG, Berlin, Germany; Caput femoris, DIZG, Berlin, Germany; Human Spongiosa, Charité Tissue Bank, Berlin, Germany) were assessed by protein extraction and analysis of the presence of MHC class 1 and 2 molecules prior to grafting. MHC concentration was measured by using enzyme-linked immunosorbent assay. RESULTS: Protein content in the allograft materials varied between 0.87 and 1.61 µg protein/mg. In the allograft Human Spongiosa, no MHC was detected, whereas in the allogeneic bone blocks Osteograft and Caput femoris MHC 1 (0.04-0.037 ng/mg graft material) and in Osteograft MHC class 2 molecules were detectable. CONCLUSIONS: The results of the present study suggest that despite thorough processing, a potential antigenicity of allografts is not eliminated. MHC molecules in allografts may sensitize the immune system.

Injury Patterns among Elite Football Players: A Media-based Analysis over 6 Seasons with Emphasis on Playing Position.

The study objective was to describe the types, localizations and severity of injuries among first division Bundesliga football players, and to study the effect of playing position on match and training injury incidence and severity, based on information from the public media. Exposure and injuries data from 1 448 players over 6 consecutive seasons were collected from a media-based register. In total, 3 358 injuries were documented. The incidence rate for match and training injuries was 11.5 per 1 000 match-hours (95% confidence interval [CI]: 10.9-12.2), and 61.4 per 100 player-seasons (95% CI: 58.8-64.1), respectively. Strains (30.3%) and sprains (16.7%) were the major injury types, with the latter causing significantly longer lay-off times than the former. Significant differences between the playing positions were found regarding injury incidence and injury burden (lay-off time per incidence-rate), with wing-defenders sustaining significantly lower incidence-rates of groin injuries compared to forwards (rate ratio: 0.43, 95% CI: 0.17-0.96). Wing-midfielders had the highest incidence-rate and injury burden from match injuries, whereas central-defenders sustained the highest incidence-rate and injury burden from training injuries. There were also significant differences in match availability due to an injury across the playing positions, with midfielders sustaining the highest unavailability rates from a match and training injury. Injury-risk and patterns seem to vary substantially between different playing positions. Identifying positional differences in injury-risk may be of major importance to medical practitioners when considering preventive measures.