1.
J Protozool
; 29(2): 239-42, 1982 May.
Article
in English
| MEDLINE
| ID: mdl-6808124
ABSTRACT
The growth inhibition of Tetrahymena furgasoni (once known as "T. pyriformis W") by C19 and C21 steroids of similar structure was measured by determining cell population at 24 h and 48 h following addition of the steroid. A cis-fusion of the A/B rings junction, unsaturation at C-1,2, or C-4,5 and carbonyl substitution all enhanced inhibition, whereas the presence of two hydroxyl groups decreased inhibition. The results indicated that the transformation of C19 and C21 steroids by this protozoon may be part of a detoxication mechanism.
Subject(s)
Androstenols/pharmacology , Growth Inhibitors , Pregnenediones/pharmacology , Tetrahymena pyriformis/growth & development , Animals , Dose-Response Relationship, Drug , Time Factors
2.
J Steroid Biochem
; 8(4): 329-34, 1977 Apr.
Article
in English
| MEDLINE
| ID: mdl-407399
3.
J Steroid Biochem
; 7(3): 177-83, 1976 Mar.
Article
in English
| MEDLINE
| ID: mdl-180334
4.
Anal Chem
; 43(12): 1712-5, 1971 Oct.
Article
in English
| MEDLINE
| ID: mdl-5130422
Subject(s)
17-Ketosteroids/analysis , Chromatography , Glucocorticoids/analysis , Autoanalysis , Methods
5.
Steroids
; 17(3): 365-75, 1971 Mar.
Article
in English
| MEDLINE
| ID: mdl-4323977
Subject(s)
17-Ketosteroids/analysis , Adrenal Cortex Hormones/analysis , Chromatography , Methods , Silicon Dioxide
6.
J Chromatogr
; 53(2): 225-32, 1970 Dec.
Article
in English
| MEDLINE
| ID: mdl-5498844
