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1.
Transplant Cell Ther ; 27(6): 502.e1-502.e6, 2021 06.
Article in English | MEDLINE | ID: mdl-33827757

ABSTRACT

Patients undergoing hematopoietic cell transplantation (HCT) experience decline in their physical activity during their transplant admission. There is limited experience with prospective monitoring of transplant recipients. We therefore measured physical activity and sleep patterns of subjects undergoing autologous and allogeneic HCT. Eighty-three patients were consented for this study. Sixty-three patients competed the study and had their physical activity prospectively assessed using the fitness-tracking device Fitbit HR. Outcomes included adherence, physical activity, readmission, hematopoietic engraftment, and 100-day survival. Sixty percent of patients (n = 37) underwent autologous HCT, and 40% (n = 26) underwent allogenic HCT. Both groups had a comparable number of steps at admission to the hospital. The number of daily steps during the study period was lower in the allogeneic group (2159 versus 3008, P = .07), as was the minimum number of steps recorded over the transplant admission (allogeneic HCT = 395 versus autologous HCT = 848, P = .01). Patients undergoing allogeneic HCT were less active on the day before discharge (1956 steps versus 3183 steps, P = .08). In multivariate analysis, physical activity was not associated with HCT-related outcomes. Patients undergoing HCT experience significant decline in their physical activity during their transplant admission that does not recover by the time of discharge. This effect can be objectively measured using fitness tracking devices.


Subject(s)
Hematopoietic Stem Cell Transplantation , Transplantation Conditioning , Exercise , Humans , Pilot Projects , Prospective Studies , Sleep , Transplantation, Homologous
2.
Cleve Clin J Med ; 2020 May 05.
Article in English | MEDLINE | ID: mdl-32371560

ABSTRACT

Positive airway pressure (PAP) therapy is an open system that can generate contact, droplet, and airborne COVID-19 thereby increasing the risk of transmission of COVID-19 like other procedures such as tracheal intubation, noninvasive ventilation, and cardiopulmonary resuscitation. Medically prudent recommendations have been established for home use of PAP therapy in asymptomatic patients and patients with suspected or confirmed COVID-19. Recommendations for sleep clinics and sleep laboratory activities are also discussed as well as the emergency use of PAP devices as a substitute for ventilation.

3.
J Clin Sleep Med ; 16(5): 811-815, 2020 05 15.
Article in English | MEDLINE | ID: mdl-32108569

ABSTRACT

None: The Payer Policy Review Committee of the American Academy of Sleep Medicine launched an initiative to assess the alignment between clinical practice guidelines and private payer medical policies. This article summarizes the importance of the initiative, details the scorecard development process, including an analysis of policy scores and subsequent revisions, and discusses the impact of the scorecards particularly as related to the scorecards on the clinical practice guideline for diagnosis of obstructive sleep apnea in adults. This initiative has increased communication and engagement among members of the Payer Policy Review Committee and private payers, creating opportunities to advocate on behalf of sleep medicine providers and patients with sleep disorders, encouraging payers to modify existing policies so that evidence-based care is provided to patients with sleep disorders.


Subject(s)
Sleep Apnea, Obstructive , Sleep Wake Disorders , Academies and Institutes , Adult , Humans , Policy , Sleep Apnea, Obstructive/diagnosis , Sleep Apnea, Obstructive/therapy , United States
4.
Cleve Clin J Med ; 86(9 Suppl 1): 26-33, 2019 Sep.
Article in English | MEDLINE | ID: mdl-31509501

ABSTRACT

Positive airway pressure (PAP) devices deliver a pressurized column of air to open the airway in patients with sleep apnea. For patients with moderate to severe sleep apnea, PAP therapy is the gold standard for treatment, with demonstrated improvements in daytime sleepiness and cardiovascular measures that are superior to conservative treatments. For a variety of reasons, adherence to PAP therapy is a challenge for many patients, resulting in deficits in the frequency and duration of use. To improve use and compliance to therapy, several advanced features are available to enhance comfort, pressure, and humidification factors associated with PAP devices. Patient motivation strategies such as motivational interviews, desensitization protocols, and PAP "NAPs" are also being employed to improve adherence to therapy.


Subject(s)
Continuous Positive Airway Pressure/psychology , Patient Compliance/psychology , Sleep Apnea Syndromes/psychology , Sleep Apnea Syndromes/therapy , Humans , Motivation
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