Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
Aust Vet J ; 94(10): 384-6, 2016 Oct.
Article in English | MEDLINE | ID: mdl-27671083

ABSTRACT

There are few reports of coagulation times in marsupial species. Blood samples collected from 14 Bennett's wallabies (Macropus rufogriseus) under anaesthesia during routine health assessments were analysed for prothrombin time (PT) and activated partial thromboplastin time (aPTT) using a point-of-care analyser (POC) (Abaxis VSPro®). The wallabies had an aPTT mean of 78.09 s and median of 78.1 s. The PT for all wallabies was greater than 35 s, exceeding the longest time measured on the POC. Although PT was significantly longer, aPTT was similar to the manufacturer's domestic canine reference range.


Subject(s)
Macropodidae/blood , Partial Thromboplastin Time/veterinary , Prothrombin Time/veterinary , Animals , Female , Male , Point-of-Care Systems
2.
Vet Pathol ; 46(5): 977-84, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19429991

ABSTRACT

Marked renal vascular changes, suggestive of hypertension, were present in adult western gray kangaroos (Macropus fuliginosus) from a single facility over a 14-year period. A subset of these kangaroos also had vague clinical nervous system deficits, including blindness. To characterize the vascular lesions, determine prevalence, and document other changes, case histories and archival tissue sections from 21 adult kangaroos (8 male, 13 female) that died or were euthanatized between 1994 and 2008 were reviewed. Relevant lesions included increased thickness of the renal arteriolar tunica media with smooth muscle hypertrophy and/or hyperplasia, accumulation of extracellular matrix within arterioles, increased vascular tortuosity, and varying degrees of juxtaglomerular hyperplasia. Renal tissue from two more severely affected animals was further examined by transmission electron microscopy, highlighting arteriolar endothelial cell hypertrophy and disruption of the medial architecture. Hypertrophy of arteries and arterioles in other organ systems was also present (3/21), including vessels in the brain and spinal cord of one animal with clinical neurologic signs. Four kangaroos had antemortem retinal detachment, a potential sequel of hypertension in humans and domestic mammals. The cause of these vascular lesions in this mob is uncertain. Lesions were not associated with an infectious disease process, age, underlying renal disease, or thyroid abnormalities. In the absence of other causes, hypertension was a differential. Further investigation into clinical significance and predisposing factors, such as genetics and diet, is warranted.


Subject(s)
Hypertension/veterinary , Kidney Diseases/veterinary , Macropodidae/physiology , Animals , Arterioles/physiopathology , Arterioles/ultrastructure , Female , Histocytochemistry/veterinary , Hypertension/physiopathology , Hypertrophy/physiopathology , Kidney Diseases/physiopathology , Male , Microscopy, Electron, Transmission/veterinary , Retinal Detachment/physiopathology , Retinal Detachment/veterinary , Retrospective Studies
3.
J Zoo Wildl Med ; 31(3): 329-34, 2000 Sep.
Article in English | MEDLINE | ID: mdl-11237139

ABSTRACT

Seven (three male and four female) 4-7-yr old captive servals (Felis serval) weighing 13.7 +/- 2.3 kg were used to evaluate the cardiopulmonary and anesthetic effects of combined intramuscular injections of medetomidine (47.4 +/- 10.3 microg/kg), ketamine (1.0 +/- 0.2 mg/kg), and butorphanol (0.2 +/- 0.03 mg/kg). Inductions were smooth and rapid (11.7 +/- 4.3 min) and resulted in good muscle relaxation. Significant decreases in heart rate (85 +/- 12 beats/min) at 10 min after injection and respiratory rate (27 +/- 10 breaths/min) at 5 min after injection continued throughout the immobilization period. Rectal temperature and arterial blood pressure did not change significantly. The PaO2 decreased significantly, and PaCO2 increased significantly during immobilization but remained within clinically acceptable limits. Hypoxemia (PaO2 < 60 mm Hg) was not noted, and arterial blood oxygen saturation (SaO2) was greater than 90% at all times. Relative arterial oxygen saturation (SpO2) values, indicated by pulse oximetry, were lower than SaO2 values. All animals could be safely handled while sedated. Administration of atipamezole (236.8 +/- 51.2 microg/kg half i.v. and half s.c.), an alpha2 antagonist, resulted in rapid (4.1 +/- 3 min to standing) and smooth recoveries.


Subject(s)
Adrenergic alpha-Antagonists/pharmacology , Anesthesia/veterinary , Anesthetics, Dissociative/administration & dosage , Butorphanol/administration & dosage , Carnivora , Heart/drug effects , Hypnotics and Sedatives/administration & dosage , Imidazoles/pharmacology , Ketamine/administration & dosage , Lung/drug effects , Medetomidine/administration & dosage , Animals , Animals, Zoo , Blood Gas Analysis , Butorphanol/pharmacology , Drug Combinations , Female , Heart Rate/drug effects , Hypnotics and Sedatives/pharmacology , Injections, Intramuscular/veterinary , Ketamine/pharmacology , Male , Medetomidine/pharmacology , Respiration/drug effects
SELECTION OF CITATIONS
SEARCH DETAIL
...