Color sorting and color term evolution.

When participants sort color samples into piles, Boster showed that their color groupings can resemble the "stages" of Kay & McDaniel's model of color term evolution. Boster concluded that both the unfolding of color piles in a sequential color sorting task and the unfolding of color terms according to Kay & McDaniel's model reveal how human beings understand color. If this is correct, then: (1) pile sorts should be reasonably robust across variations in the palette of colors to be sorted, as long as the palette contains good examples of Berlin & Kay's universal color categories, and (2) pile-sorting should be more related to lexical effects and less related to perceptual processes governed by similarity judgments alone. We report three studies on English speakers and Somali speakers (Study 1 only), where participants sorted colors into 2…6 piles. The three studies used varying numbers of palette colors (25, 30, or 145 colors) and varying chromaticity schemes (mainly hue, widely-separated in hue and lightness, or densely distributed at high chroma). We compared human sorting behavior to Kay & McDaniel's model and to the "optimal" patterns of color sorting predicted by Regier's well-formedness statistic, which quantifies the perceived similarity between colors. Neither hypothesis is confirmed by the results of our studies. Thus, we propose that color sorts are determined by pragmatic influences based on heuristics that are inspired by the palette of colors that are available and the task that the viewer is asked to perform.

Vision-related quality of life in adults with severe peripheral vision loss: a qualitative interview study.

BACKGROUND: Existing patient-reported outcome (PRO) measures may not be relevant to the full range of functional and vision-related quality of life (VR-QOL) concerns of individuals with vision impairment due to severe peripheral field loss (PFL). Measurement of VR-QOL in severe PFL is important in order to determine the effectiveness of vision rehabilitation interventions for this population. The purpose of this study was to characterize the impact of severe PFL due to retinitis pigmentosa (RP) and glaucoma on VR-QOL as the initial phase in the development of a novel PRO measure. METHODS: Individuals with severe PFL due to RP or glaucoma were recruited from the Kellogg Eye Center and the Association for the Blind and Visually Impaired. Participants completed semi-structured qualitative interviews, the Impact of Vision Impairment (IVI) questionnaire and the RAND 36-Item Health Survey. Interviews were analyzed by two coders using thematic analysis. A matrix analysis was conducted to compare VR-QOL by cause of severe PFL. Sample size was determined by thematic saturation. RESULTS: The study included 37 participants (19 RP, 18 glaucoma). Median best-corrected visual acuity for those with RP and glaucoma was 20/40 and 20/27.5, while Pelli-Robson contrast sensitivity was 1.2 log contrast sensitivity (logCS) and 1.1 logCS, respectively. Median domain scores on the IVI (reading, mobility, well-being) ranged from a low of - 0.2 to a high of 0.7 logits in those with RP and from 0.5 to 1.2 logits in those with glaucoma. Qualitative interviews identified six VR-QOL themes relevant across participants with both RP and glaucoma, including activity limitations, driving, emotional well-being, reading, mobility, and social function. VR-QOL concerns were largely consistent among those with severe PFL due to RP and glaucoma. These overarching themes contained content relevant to specific challenges related to severe PFL. CONCLUSIONS: There are commonly occurring VR-QOL concerns among individuals with severe PFL due to RP and glaucoma. The outlined themes will serve as the basis for development of the Low Vision Severely Constricted Peripheral Eyesight (LV-SCOPE) Questionnaire.

Testing the Cross-Cultural Generality of Hering's Theory of Color Appearance.

This study examines the cross-cultural generality of Hering's (1878/1964) color-opponent theory of color appearance. English-speaking and Somali-speaking observers performed variants of two paradigms classically used to study color-opponency. First, both groups identified similar red, green, blue, and yellow unique hues. Second, 25 English-speaking and 34 Somali-speaking observers decomposed the colors present in 135 Munsell color samples into their component Hering elemental sensations-red,green,blue, yellow, white, and black-or else responded "no term." Both groups responded no term for many samples, notably purples. Somali terms for yellow were often used to name colors all around the color circle, including colors that are bluish according to Hering's theory. Four Somali Grue speakers named both green and blue elicitation samples by their term for green. However, that term did not name the union of all samples called blue or green by English speakers. A similar pattern was found among three Somali Achromatic speakers, who called the blue elicitation sample black or white. Thus, color decomposition by these Somali-speaking observers suggests a lexically influenced re-dimensionalization of color appearance space, rather than a simple reduction of the one proposed by Hering. Even some Somali Green-Blue speakers, whose data were otherwise similar to English, showed similar trends in yellow and blue usage. World Color Survey data mirror these results. These within- and cross-cultural violations of Hering's theory do not challenge the long-standing view that universal sensory processes mediate color appearance. However, they do demonstrate an important contribution of language in the human understanding of color.

Does feature integration affect resolution of multiple simultaneous forms of ambiguity?

Ambiguity resolution, perceptual grouping, and feature integration all occur seamlessly and subconsciously. When multiple regions of an image share ambiguous features, perceptual grouping can yield an integrated object percept rather than one of multiple objects, each with its individual features. Here, perceptual resolution and grouping of chromatically rivalrous Necker cubes were investigated in three experiments to determine the principles that underlie these coherent percepts. The first experiment showed perceptual grouping beyond independent resolution of each cube's color and orientation, but the second experiment did not show grouping greater than expected from separate color- and orientation-grouping processes. The third experiment found no reliable difference in grouping when two features (color and orientation) were part of the same object versus when they were distributed across separate objects. These findings fail to support a role for feature conjunctions in grouping objects with multiple ambiguous features.

The modern Japanese color lexicon.

Despite numerous prior studies, important questions about the Japanese color lexicon persist, particularly about the number of Japanese basic color terms and their deployment across color space. Here, 57 native Japanese speakers provided monolexemic terms for 320 chromatic and 10 achromatic Munsell color samples. Through k-means cluster analysis we revealed 16 statistically distinct Japanese chromatic categories. These included eight chromatic basic color terms (aka/red, ki/yellow, midori/green, ao/blue, pink, orange, cha/brown, and murasaki/purple) plus eight additional terms: mizu ("water")/light blue, hada ("skin tone")/peach, kon ("indigo")/dark blue, matcha ("green tea")/yellow-green, enji/maroon, oudo ("sand or mud")/mustard, yamabuki ("globeflower")/gold, and cream. Of these additional terms, mizu was used by 98% of informants, and emerged as a strong candidate for a 12th Japanese basic color term. Japanese and American English color-naming systems were broadly similar, except for color categories in one language (mizu, kon, teal, lavender, magenta, lime) that had no equivalent in the other. Our analysis revealed two statistically distinct Japanese motifs (or color-naming systems), which differed mainly in the extension of mizu across our color palette. Comparison of the present data with an earlier study by Uchikawa & Boynton (1987) suggests that some changes in the Japanese color lexicon have occurred over the last 30 years.

Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant.

In order to assess the contribution of a central clock in the hypothalamic suprachiasmatic nucleus (SCN) to circadian behavior and the organization of peripheral clocks, we generated forebrain/SCN-specific Bmal1 knockout mice by using floxed Bmal1 and pan-neuronal Cre lines. The forebrain knockout mice showed >90% deletion of BMAL1 in the SCN and exhibited an immediate and complete loss of circadian behavior in constant conditions. Circadian rhythms in peripheral tissues persisted but became desynchronized and damped in constant darkness. The loss of synchrony was rescued by light/dark cycles and partially by restricted feeding (only in the liver and kidney but not in the other tissues) in a distinct manner. These results suggest that the forebrain/SCN is essential for internal temporal order of robust circadian programs in peripheral clocks, and that individual peripheral clocks are affected differently by light and feeding in the absence of a functional oscillator in the forebrain.

Evaluation of eight plasma proteins as candidate blood-based biomarkers for malignant gliomas.

Eight brain-derived proteins were evaluated regarding their potential for further development as a blood-based biomarker for malignant gliomas. Plasma levels for glial fibrillary acidic protein, neurogranin, brain-derived neurotrophic factor, intracellular adhesion molecule 5, metallothionein-3, beta-synuclein, S100 and neuron specific enolase were tested in plasma of 23 patients with high-grade gliomas (WHO grade IV), 11 low-grade gliomas (WHO grade II), and 15 healthy subjects. Compared to the healthy controls, none of the proteins appeared to be specific for glioblastomas. However, the data are suggestive of higher protein levels in gliosarcomas (n = 2), which may deserve further exploration.