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Presse Med ; 34(15): 1082-3, 2005 Sep 10.
Article in French | MEDLINE | ID: mdl-16334886

ABSTRACT

INTRODUCTION: Primary epidural lymphoma is generally manifested by isolated epidural involvement. On rare occasions it can lead to cauda equina syndrome. CASE: A 56-year-old man was hospitalized for lumbago, weakness in the legs and sphincter problems. A dorsolumbar MRI revealed that the anterior and posterior peridural space from D11 to L3 was filled by a mass compressing the marrow and compacting the roots. The L2 to L4 laminectomy revealed an extradural tissue leading to the diagnosis of large B-cell lymphoma. Metastatic workup demonstrated unremarkable findings. DISCUSSION: Primary epidural lymphoma accounts for less than 10% of epidural tumours and less than 1% of non-Hodgkin lymphomas. Its clinical manifestations are related to the tumoral process or involvement of medullar vessels. It can be, but rarely is, manifested by cauda equina syndrome. Diagnosis is based on histological analysis of tissue taken during the decompression laminectomy. Prognosis is relatively good.


Subject(s)
Epidural Neoplasms/complications , Lymphoma, B-Cell/complications , Polyradiculopathy/etiology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Combined Modality Therapy , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Epidural Neoplasms/diagnosis , Epidural Neoplasms/drug therapy , Epidural Neoplasms/radiotherapy , Humans , Laminectomy , Lumbar Vertebrae , Lymphoma, B-Cell/diagnosis , Lymphoma, B-Cell/drug therapy , Lymphoma, B-Cell/radiotherapy , Magnetic Resonance Imaging , Male , Middle Aged , Polyradiculopathy/diagnosis , Prednisone/therapeutic use , Prognosis , Radiotherapy Dosage , Remission Induction , Vincristine/therapeutic use
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