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5.
Clin Rheumatol ; 25(3): 409-11, 2006 May.
Article in English | MEDLINE | ID: mdl-16220226

ABSTRACT

Bone pain due to bone metastases is a frequent presenting symptom of lung cancer. However, sternal metastases are unusual. We report two patients with inflammatory sternal metastases mimicking osteitis and indicating lung cancer. Chest computed tomography scan showed lytic lesion of the sternal manubrium invading anterior soft tissue. Diagnosis relied on histological examination of sternal biopsy and negative bacteriologic cultures. Local radiotherapy resulted in resolution of local signs.


Subject(s)
Adenocarcinoma/secondary , Lung Neoplasms/pathology , Neoplasm Metastasis/pathology , Sternum/pathology , Thoracic Neoplasms/secondary , Adenocarcinoma/diagnostic imaging , Aged , Diagnosis, Differential , Humans , Lung Neoplasms/diagnostic imaging , Male , Osteitis/pathology , Radiotherapy , Sternum/radiation effects , Thoracic Neoplasms/diagnostic imaging , Thoracic Neoplasms/radiotherapy , Tomography, X-Ray Computed , Treatment Outcome
6.
Presse Med ; 33(3): 167-9, 2004 Feb 14.
Article in French | MEDLINE | ID: mdl-15029028

ABSTRACT

INTRODUCTION: Chylous ascitis is a rare form of ascitis, characterised by a milky, triglyceride-rich, liquid. It is due to an interruption in the lymphatic system due either to an obstruction or to a post-traumatic wound. We report a case of revealing a non-Hodgkin lymphoma. OBSERVATION: A 71 Year-old man consulted for abdominal distension attributed to a chylous ascitis. Peripheral adenopathies were palpable. The abdominal scan revealed voluminous lumbar-aortal adenopathies. The diagnosis of grade IV (Ann Arbor classification) centro-follicular non-Hodgkin lymphoma was retained. The ascitis disappeared following chemotherapy. COMMENTS: Chylous ascitis is an uncommon complication of lymphomas, although representing the main cause in adults in developed countries. The underlying mechanism is an obstruction to sub-diaphragmatic draining lymphatic due to lymphomatous infiltration. Hyperalimentation, a low, dietary restriction of long-chain triglycerides or peritoneovenous shuntings are ineffective. CONCLUSION: Chylous ascitis is a rare complication of lymphomas, secondary to the obstruction of the abdominal draining lymphatics. Treatment is the same as that of a hematologic malignancy.


Subject(s)
Chylous Ascites/etiology , Lymphoma, Follicular/diagnosis , Aged , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Chylous Ascites/diagnosis , Chylous Ascites/diagnostic imaging , Humans , Lymphoma, Follicular/complications , Lymphoma, Follicular/diagnostic imaging , Lymphoma, Follicular/drug therapy , Male , Radiography, Abdominal , Remission Induction , Tomography, X-Ray Computed
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