1.
Chem Commun (Camb)
; 51(1): 77-80, 2015 Jan 04.
Article
in English
| MEDLINE
| ID: mdl-25383663
ABSTRACT
Succession of C-H activation and C-C activation was achieved by using a single rhodium(III) catalyst. Vinylcyclopropanes were used as versatile coupling partners. Mechanistic studies suggest that the olefin insertion step is rate-determining and a facile ß-carbon elimination is involved, which represents a novel ring opening mode of vinylcyclopropanes.
Subject(s)
Carbon/chemistry , Cyclopropanes/chemistry , Hydrogen/chemistry , Rhodium/chemistry , Catalysis , Coordination Complexes/chemistry , Cyclization , Oxidation-Reduction , Stereoisomerism , Vinyl Compounds/chemistry
2.
Org Lett
; 16(24): 6412-5, 2014 Dec 19.
Article
in English
| MEDLINE
| ID: mdl-25438098
ABSTRACT
A rhodium(III)-catalyzed C-H direct allylation reaction with 4-vinyl-1,3-dioxolan-2-ones has been developed. The reaction provides a facile and stereoselective access to substituted-(E)-allylic alcohols under mild and redox-neutral reaction conditions. Olefinic C-H activation is applicable, giving multifunctionalized skipped dienes in good yields. Minimal double-bond migration was observed.