[Medico-social and economic aspects of the rehabilitation of patients with laryngeal cancer]. / Mediko-sotsial'nye i ékonomicheskie aspekty reabilitatsii bol'nykh rakom gortani.

The results of therapy and rehabilitation of the target and control groups of patients with laryngeal cancer, each consisting of 70 people, demonstrated that the method of reconstructive subtotal resection of the larynx as compared to its extirpation was efficient and advantageous in medical, social and economic terms. The advantages of the modified method were verified clinically and statistically. In the target group every other patient and in the control group only one out of four patients regained their normal work capacity. The expenses for research and development paid off within a year.

[Inhibitory effect of serum on the phagocytic activity of macrophages in vitro]. / Ugnetaiushchee deistvie syvorotki krovi na fagotsitarnuiu aktivnost' makrofagov in vitro.

The effect of blood sera obtained from sick and healthy persons on the phagocytic activity of mouse macrophages has been studied by means of in vitro tests. The study was made on blood serum samples taken from patients with diseases owing their pathogenesis largely to the role of macrophages, such as hemoblastosis (acute leukosis, myeloleukemia, erythremia), cancer of the larynx, parasitic diseases (acute and chronic opisthorchiasis, schistosomiasis). These patients were found to have humoral factors suppressing the phagocytic activity of mouse macrophages in vitro accumulated in their blood. The test allowing to evaluate the level of humoral antimacrophage suppressants has been developed. The formation of these mediators is supposed to occur in the spleen, as the suppressant action of blood serum disappears after splenectomy.