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1.
Addict Behav ; 19(1): 13-22, 1994.
Article in English | MEDLINE | ID: mdl-8197889

ABSTRACT

In the current study, 34 smokers were treated in a smoking cessation program that involved either a scheduled smoking procedure, or a minimal contact self-help treatment control. The interval smoking program consisted of baseline, cessation, and relapse prevention phases. During baseline, subjects self-monitored smoking and the total hours spent awake. During a 3-week cessation period, the scheduled smoking group progressively increased their intercigarette interval, thereby gradually reducing their total daily intake of nicotine. Smokers were expected to quit on a target date set at the end of this period. Cognitive behavioral interventions and relapse prevention training consisted of behavioral rehearsal of nonsmoking skills in a relapse prone environment. Control subjects were given the American Cancer Society "I Quit Kit", and provided subsequent discussion of its use. The results showed that 53% and 41% of the scheduled smoking group was abstinent at the 6- and 12-month follow-up points, respectively. Controls averaged only 6% for the same periods. Scheduled smoking may be a useful addition to a multicomponent treatment program and further study appears warranted to determine the saliency of the treatment features.


Subject(s)
Aftercare/methods , Behavior Therapy/methods , Smoking Cessation/methods , Smoking Prevention , Adult , Aftercare/psychology , Cognitive Behavioral Therapy/methods , Female , Humans , Male , Middle Aged , Nicotine/administration & dosage , Pamphlets , Recurrence , Reinforcement Schedule , Self Care/psychology , Smoking/psychology , Smoking Cessation/psychology , Social Environment , Treatment Outcome
2.
Biol Psychol ; 28(3): 251-64, 1989 Jun.
Article in English | MEDLINE | ID: mdl-2590702

ABSTRACT

The purpose of this study was to assess nicotine regulation among "heavy" and "light" smokers. Previous studies supporting the nicotine regulation model of smoking behavior have suggested that smokers compensate for a reduction in the amount of nicotine available in their cigarette by altering smoking frequency, puff volume, or other aspects of smoking topography. However, little is known about a smoker's decision to smoke a specific cigarette, and the concurrent changes in their blood nicotine. Manipulation of nicotine levels in the blood could play a critical role in smoking maintenance, by regulating the extent and quality of the CNS effects of smoking. In this study, 24 heavy and light smokers (cotinine above or below 260 ng/ml) smoked high- (1.0 mg) or low- (0.5 mg) dose nicotine cigarettes while watching non-stressful movies. Blood nicotine was assessed before and after smoking a preload and free operant cigarette. The results showed that blood nicotine levels after smoking the free operant cigarette were significantly more consistent (lower standard error) for the heavy smokers, following a low dose, as opposed to a high-dose preload. Light smokers showed a non-significant trend towards being more consistent when the high-dose nicotine preload was used. This suggests that heavy smokers may have maximized their dose of nicotine whenever available nicotine was in relatively short supply (low dose condition). However, light smokers may have minimized their exposure when available nicotine was relatively more plentiful (high dose condition).


Subject(s)
Arousal/drug effects , Nicotine/administration & dosage , Smoking/psychology , Social Environment , Adult , Cotinine/pharmacokinetics , Dose-Response Relationship, Drug , Humans , Male , Nicotine/pharmacokinetics , Smoking/blood
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