1.
Beilstein J Org Chem
; 16: 1936-1946, 2020.
Article
in English
| MEDLINE
| ID: mdl-32802210
ABSTRACT
The selective ring-opening reaction of fluoroalkylidene-oxetanes was directed by the presence of the fluorine atom, enabling a two-step access to tetrasubstituted fluoroalkenes with excellent geometry control. Despite its small van der Waals radii electronic, rather than steric influences of the fluorine atom governed the ring-opening reaction with bromide ions, even in the presence of bulky substituents.