ABSTRACT
Primary malignant melanoma of the common bile duct is rare. Only seven cases have been described in the literature. Diagnosis is based on failure to find another primary site, histological examination with electron microscopy, and immunohistochemical tests. We describe a new case of primary malignant melanoma of the biliary tract and present a review of previous reports.
Subject(s)
Common Bile Duct Neoplasms/pathology , Melanoma/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Carboplatin/administration & dosage , Cholangiopancreatography, Magnetic Resonance , Common Bile Duct Neoplasms/diagnostic imaging , Dacarbazine/administration & dosage , Fatal Outcome , Gallbladder Neoplasms/secondary , Humans , Interferon alpha-2 , Interferon-alpha/administration & dosage , Lymphatic Metastasis , Male , Melanoma/diagnostic imaging , Melanoma/secondary , Microscopy, Electron , Middle Aged , Palliative Care , Recombinant Proteins , Splenic Neoplasms/secondary , Stomach Neoplasms/secondary , UltrasonographyABSTRACT
El melanoma maligno primario del colédoco es una entidad rara. Sólo se han descrito 7 casos en la bibliografía. El diagnóstico se basa en ausencia de otra localización que pudiera considerarse primaria, en el examen de microscopia electrónica y en el estudio inmunohistoquímico. Describimos un nuevo caso de melanoma maligno primario del conducto biliar y presentamos una revisión de los casos previamente publicados
Primary malignant melanoma of the common bile duct is rare. Only seven cases have been described in the literature. Diagnosis is based on failure to find another primary site, histological examination with electron microscopy, and immunohistochemical tests. We describe a new case of primary malignant melanoma of the biliary tract and present a review of previous reports
Subject(s)
Male , Humans , Melanoma/pathology , Common Bile Duct Neoplasms/pathology , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Carboplatin/administration & dosage , Cholangiopancreatography, Endoscopic Retrograde , Dacarbazine/administration & dosage , Fatal Outcome , Interferon-alpha/administration & dosage , Lymphatic Metastasis , Melanoma/secondary , Melanoma , Microscopy, Electron , Palliative Care , Common Bile Duct Neoplasms , Gallbladder Neoplasms/secondary , Stomach Neoplasms/secondary , Splenic Neoplasms/secondaryABSTRACT
BACKGROUND: The technological progress applied to laparoscopic surgery has facilitated the introduction of the technique of cholecystectomy following this new method. METHODS: The results of a group of 200 patients with cholelithiasis who had undergone laparoscopic cholecystectomy are presented. Twenty-eight patients (14%) present complicated cholelithiasis, from a technical point of view, since they were carriers of cholecystitis or had a scleroatrophic gallbladder. Only 7.5% of all of the patients attended were diagnosed of choledocholithiasis. RESULTS: Operating time was similar to that employed for cholecystectomies by laparotomy (51 min in uncomplicated surgery and one hour and a half for complications). Among the results which may be emphasized is short postoperative hospitalization (less than 2 days), even when patients submitted to other operations during the same anesthesia are included, in addition to prompt reinsertion to daily activities. Moreover, the low rate of complications (5.5%) must be underlined and the lack of notoriety as well as the low rate of readmissions. CONCLUSIONS: The good results obtained throughout the world following the use of laparoscopic cholecystectomy have placed this procedure as minimal invasive surgery, which, due to the notable reduction in surgical trauma, postoperative pain and fewer complications this procedure has become less uncomfortable for the patient.
