ABSTRACT
Basing on the 30-year experience of prof. Yu.A. Nesterenko differential method of surgical treatment for inguinal hernias was worked out. The choice of surgical technique was based on the results of intra-operative revision of inguinal canal. Single-layer plasty of posterior wall was applied in case of insignificant destruction of tendinous structures; Shouldice plasty--in case of moderate changes; Moran plasty--in case of marked destruction, Lichtenstein plasty--in case of complete inguinal canal destruction. Analysis of long-term results showed low frequency of hernia relapses (1.4%) that can be compared with indices in specialized herniologic centers.
Subject(s)
Decision Making , Hernia, Inguinal/surgery , Plastic Surgery Procedures/methods , Surgical Flaps , Surgical Mesh , Female , Follow-Up Studies , Humans , Male , Retrospective Studies , Time Factors , Treatment OutcomeABSTRACT
The results of treatment of 1,320 patients with acute pancreatitis were analysed, 460 of them had the destructive form of the disease. The high significance of multicomponent etiopathogenetic treatment is demonstrated. The importance of etiotropic treatment with the application of endoscopic interventions, as well as treatment with cytostatics is emphasized. Timely combined use of these methods prevents a progressive uncontrolled course, and reduces the volume of treatment and its duration. The authors also discuss the first experience in nontraditional management of patients with postnecrotic cavitary complications of pancreonecrosis by the aspiration "closed" method with the use of ultrasound.
Subject(s)
Antineoplastic Agents/therapeutic use , Pancreatitis/therapy , Sorption Detoxification , Sphincterotomy, Endoscopic , Acute Disease , Combined Modality Therapy , Drainage , Humans , Pancreatitis/diagnosis , Pancreatitis/mortalityABSTRACT
The article analyses certain indicators of immune reactivity in 67 patients with different forms of pancreatitis. Lower reactivity of the organism in destructive pancreatitis determines the necessary use of immune modulating therapy in the complex treatment of this disease and purulent complications. In patients with high risk of pyo-septic complications the administration of cytostatics is not indicated.
Subject(s)
Levamisole/therapeutic use , Pancreatitis/drug therapy , T-Lymphocytes/immunology , Acute Disease , Adjuvants, Immunologic , Adult , Female , Humans , Male , Middle Aged , Pancreatitis/immunologyABSTRACT
The results of the studies of morphological changes in the pancreas during intraaortal injections of various 5-fluorouracil doses to 44 dogs are reported. It was experimentally established that intraaortal injection of 10 mg 5-fluorouracil per kg of mass for 3 days caused the delay in albumin-synthesizing organella function, without damaging organellas as such. Administration of a cytostatic in a dose of 15 mg per kg of mass did not only cause a drastic decline in the synthesizing activity of cells in acinar parenchyma, but also induced intracellular lesions.
