[Dependence of the specific activity of antistaphylococcal immunoglobulin on the degree of its fragmentation]. / Izuchenie zavisimosti spetsificheskoi aktivnosti antistafilokokkovogo immunoglobulina ot stepeni fragmentatsii.

In vitro experiments have revealed no perceptible decrease in the content of antitoxic antibodies to alphastaphylolysin in the preparations of antistaphylococcal immunoglobulin, containing 13-50% of Fab-fragments. These data confirm the necessity of controlling the molecular composition of the preparations of antistaphylococcal IgG by physico-chemical methods with the aim to evaluate their quality, as the fragmented preparations are rapidly eliminated from a human body.

[Antigenic characteristics of immunoglobulin preparations]. / Antigennaia kharakteristika preparatov immunoglobulinov.

A comparative study of the content of serum protein antigens in 156 batches of human immunoglobulin preparations, produced from placental material and donor plasma in the USSR and Bulgaria, has been made by means of immune electrophoresis. The results thus obtained indicate that immunoelectrophoretic analysis may be used for the additional characteristic of the antigenic structure of immunoglobulin preparations, as well as for evaluating the degree of the purification of immunoglobulin from nonspecific serum proteins in the process of the production of commercial preparations.