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Infection ; 49(1): 177-180, 2021 Feb.
Article in English | MEDLINE | ID: mdl-32876896

ABSTRACT

BACKGROUND: The diagnosis of cutaneous leishmaniasis (CL) is often difficult because of the diversity of clinical presentations, its often-misleading appearance and the very long incubation period (time between the endemic stay and the onset of skin lesions). CASE: We report the case of an otherwise healthy 67-year-old man who presented with inflammatory skin lesions on the scalp and face for the past 7 years. The lesions were first mistaken as cutaneous sarcoidosis, mycobacterial infection, and cutaneous lymphoma. Finally, the diagnosis was made by RT-PCR analysis on a punch-biopsy specimen, which was positive for Leishmania infantum. DISCUSSION AND CONCLUSION: To date, the choice of treatment for complex cutaneous leishmaniases is based on the Leishmania species. Our patient successfully responded to liposomal amphotericin B.


Subject(s)
Leishmaniasis, Cutaneous , Aged , Amphotericin B/therapeutic use , Antiprotozoal Agents/therapeutic use , Biopsy , Diagnosis, Differential , Face/parasitology , Face/pathology , Humans , Leishmania infantum/genetics , Leishmania infantum/isolation & purification , Leishmaniasis, Cutaneous/diagnosis , Leishmaniasis, Cutaneous/drug therapy , Leishmaniasis, Cutaneous/parasitology , Leishmaniasis, Cutaneous/pathology , Male , Scalp/parasitology , Scalp/pathology , Skin/parasitology , Skin/pathology
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