Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
Appl Radiat Isot ; 109: 261-263, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26653211

ABSTRACT

(124)I is a radionuclide used in the diagnosis of tumors. The National Health Agency requires identification and activity measurement of impurities. Using gamma spectrometry with an efficiency calibrated high-purity germanium detector, impurities (125)I and (126)I in an (1)(24)I production sample were identified. Activity ratios of (125)I and (126)I to (124)I were approximately 0.5% and 98%, respectively.


Subject(s)
Drug Contamination/prevention & control , Iodine Radioisotopes/analysis , Iodine Radioisotopes/standards , Radiometry/methods , Radiometry/standards , Spectrometry, Gamma/standards , Brazil , Reproducibility of Results , Sensitivity and Specificity , Spectrometry, Gamma/methods
2.
Appl Radiat Isot ; 109: 236-241, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26688362

ABSTRACT

Since the inception of its proficiency test program to evaluate radionuclide measurement in hospitals and clinics, the National Metrology Laboratory of Ionizing Radiation-LNMRI, that represents Brazilian National Metrology Institute (NMI) for ionizing radiation has expanded its measurement and calibration capability. Requirements from the National Health Surveillance Agency from Ministry of Health (ANVISA), to producers of radiopharmaceuticals provided an opportunity to improve the full traceability chain to the highest level. Fluorodeoxyglucose (FDG-(18)F) is the only radiopharmaceutical simultaneously produced by all Brazilian radiopharmaceutical production centers (RPCs). By running this proficiency test, LNMRI began to provide them with the required traceability. For evaluation, the ratio of RPC to reference value results and ISO/IEC17043:2010 criteria were used. The reference value established as calibration factor on the secondary standard ionization chamber was obtained from three absolute measurements systems, and routinely confirmed in each round of proficiency test by CIEMAT/NIST liquid scintillation counting. The γ-emitting impurities were checked using a High-Purity Germanium (HPGe) detector. The results show that Brazilian RPCs are in accordance with (accuracy within ±10%) the Brazilian standard for evaluation of measurements with radionuclide calibrators (CNEN NN 3.05., 2013). Nevertheless, the RPCs should improve the methodology of uncertainty estimates, essential when using the statistical criteria of ISO/IEC 17043 standard, in addition to improving accuracy to levels consistent with their position in the national traceability chain.


Subject(s)
Fluorine Radioisotopes/analysis , Fluorine Radioisotopes/standards , Public Sector/standards , Radiometry/methods , Radiometry/standards , Brazil , Reference Standards , Reproducibility of Results , Sensitivity and Specificity
3.
Radiat Prot Dosimetry ; 144(1-4): 310-3, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21051429

ABSTRACT

In October 2009, the International Atomic Energy Agency (IAEA) sponsored an intercomparison exercise of surface contamination monitoring equipment, which was held at the Laboratório Nacional de Metrologia das Radiações Ionizantes, from the Instituto de Radioproteção e Dosimetria, IRD/CNEN, Rio de Janeiro. This intercomparison was performed to evaluate the calibration accessibility in Latin America and the Caribbean. Thirteen countries within the region and IAEA have sent instruments to be compared, but only five countries and IAEA were considered apt to participate. Analysis of instruments, results and discussions are presented and recommendations are drawn.


Subject(s)
Radiation Monitoring/instrumentation , Radiation Protection/instrumentation , Radiometry/instrumentation , Calibration , Caribbean Region , Equipment Contamination , Humans , International Agencies , International Cooperation , Latin America , Models, Statistical , Radiation Monitoring/methods , Radiation Protection/methods , Radiometry/methods , Surface Properties
SELECTION OF CITATIONS
SEARCH DETAIL
...