ABSTRACT
OBJECTIVE: In this report, we describe the abuse of fluoxetine (an antidepressant) in two patients who had histories of substance abuse. MATERIAL AND METHODS: Specific details of the stimulant effects of fluoxetine, used in excessive dosages and in conjunction with other drugs, are discussed. RESULTS: After hospitalization, our two patients were able to discontinue use of fluoxetine and had improved mentation. CONCLUSION: Although the mechanism for this phenomenon is unknown, we postulate that drug craving and behavioral factors are involved.
Subject(s)
Fluoxetine , Substance-Related Disorders , Adult , Female , Humans , Male , Substance-Related Disorders/psychologyABSTRACT
A new technique for quantitative assessment of rose bengal staining in ocular surface disorders is described. The globe is divided into 16 quadrants which represent clinically important regions of the eye. Each quadrant is graded numerically for intensity and area of rose bengal staining. This simple grading system facilitates mathematical study and computer analysis of ocular surface disease.
