ABSTRACT
The LSU reciprocation-gait orthosis is a lightweight bracing device that gives structural support to the lower trunk and lower limbs of the paralytic patient while allowing, through a cable-coupling system, proper hip joint motion for walking.
Subject(s)
Creatine Kinase/blood , Fetal Diseases/diagnosis , Muscular Dystrophies/diagnosis , Umbilical Cord/enzymology , Abortion, Induced , Blood , Child , Clinical Enzyme Tests , Female , Fetus/blood supply , Gestational Age , Humans , Male , Muscular Dystrophies/genetics , Pregnancy , Sex Chromosome Aberrations/diagnosisSubject(s)
Eye Manifestations , Lupus Erythematosus, Systemic/diagnosis , Optic Neuritis/etiology , Adult , Child , Diagnostic Errors , Female , Humans , Lupus Erythematosus, Systemic/complications , Lupus Erythematosus, Systemic/drug therapy , Lupus Erythematosus, Systemic/pathology , Multiple Sclerosis/diagnosis , Optic Nerve/pathology , Optic Neuritis/pathology , Prednisone/therapeutic use , Spinal Cord/pathologyABSTRACT
The finding of a relative absence of degeneration and regeneration in a muscle biopsy taken at 2½ weeks of age from a boy who later showed the florid pathological changes of preclinical Duchenne muscular dystrophy prompted a review of muscle biopsies taken from boys in the preclinical and early clinical stages of this disease. Only one other biopsy obtained in the first year of life was available. In this, taken at 2 months, there were active changes present. These findings suggest that biopsies taken to detect preclinical cases should not be performed at less than 2 months of age, and raise the possibility of the existence of a stage in Duchenne muscular dystrophy before active degeneration when the muscle shows little or no change on light microscopy.
