ABSTRACT
Objetivo: El objetivo principal de este trabajo es ofrecer datos objetivos de los cambios experimentados por un grupo de 30 niños con parálisis cerebral, de distinta tipología y grado de afectación, tras su participación en un programa intensivo de rehabilitación basado en el Método Petö o Educación Conductiva. Material y métodos: Los niños fueron explorados en dos momentos, al inicio y al final de las cinco semanas de tratamiento intensivo. En la primera evaluación se cumplimentó la historia clínica y se realizó una exploración motriz, cognitiva y adaptativa. En la segunda evaluación se repitió la exploración de la motricidad y de las destrezas adaptativas. La exploración motriz se realizó a través de la Gross Motor Function Measure (GMFM) de Russell, Rosenbaum, Avery y Lane (2002) y fue grabada en video. Resultados: El análisis de las puntuaciones obtenidas en la GMFM indica que un 70% de los niños con PC evaluados experimentan progresos significativos en su patrón motor grueso. También es interesante considerar otros aspectos positivos, como son la motivación y el interés que presentan estos niños durante el tratamiento a pesar de su intensidad
Objetive: To evaluate the clinical progress in a sample of 30 children with Cerebral Palsy, reciving an intensive therapy program of rehabilitation based on Conductive Education (Petö Program). Material and methods: Thirty children were examinated twice, at the beginning and at the end of an intensive 5- week program of Conductive Education therapy. We adressed motor examination and cognitive and adaptative function. Motor examination was assessed by means of Gross Motor Function Measure (GMFM) by Russell, Rosenbaum, Avery an Lane (2002), and video filmed. Results: Seventy per cent of children showed significant progress in their gross motor patern after treatment, not attributed to natural evolution of Cerebral Palsy
Subject(s)
Male , Female , Child, Preschool , Child , Humans , Cerebral Palsy/therapy , Cognitive Behavioral Therapy/methods , Patient Education as Topic/methods , Evaluation of Results of Therapeutic Interventions , Motor Skills Disorders/rehabilitation , Treatment OutcomeABSTRACT
BACKGROUND: Increasingly growing evidence exists of the involvement of oxidative stress mechanisms in Parkinson's disease. Lower levels of GSH in the sustantia nigra, an increase in iron buildup, an increase in the byproducts of lipid peroxidation and alterations in the mitochondrial complex I have been described. However, few studies have been made of levels of antioxidants in the peripheral bloodstream and of the influence of the intake of nutrients on the development of this disease. METHODS: In a group of 79 patients afflicted with idiopathic Parkinson's disease and a control group comprised of 107 subjects, compared by age, sex and place of residence, the lowered levels in the plasma of glutathione (GSH), malon dialdehyde (MDA), uric acid, tocophenol, beta-carotene, lycopene and different iron metabolism parameters were studied. Likewise, the intake of certain antioxidants was estimated based on a dietary survey. RESULTS: Significant differences (p < or = 0.001) were found in the plasma levels of GSH between cases (0.10 mumol/ml +/- 0.06) and controls (0.29 mumol/ml +/- 0.12). Likewise, the plasma levels of uric acid were lower (p < or = 0.05) in the cases (4.96 mg/ml +/- 1.96) than in the control groups (5.39 mg/ml +/- 1.13). No significant difference was found in the plasma levels of MDA, tocopherol, beta-carotene and lycopene. With regard to iron metabolism, significantly higher ferritine and transferrin values were found in the patients with EP than in the control group, showing a lower transferrin saturation percentage (p < or = 0.05). The iron showed no significant changes between cases and control groups. CONCLUSIONS: The results of this study support the possible involvement of oxidative stress in the pathogenesis of Parkinson's disease and reveal, in turn, alterations in some peripheral blood parameters in keeping with known findings in the sustantia nigra.
