[The evaluation of a threat of osteoporosis among the employees at the pharmaceutical firm "Jelfa" in Jelenia Góra]. / Ocena zagrozenia osteoporoza wsród zalogi Przedsiebiorstwa Farmaceutycznego "Jelfa" S.A. w Jeleniej Górze.

Nine hundred eight workers of Pharmaceutical Firm "Jelfa" at Jelenia Góra at the age over 35 were examined. Examinations were done in the form of inquiry, what gave all necessary data about age, weight, feeding habits, kind of work, fractures in the past and menstruations in women. The information were elaborated together with densitometric tests. We measured bone density (BMD) with densimeter DTX-200 (Osteometer) in the distal part of not dominant antebrachium. 23% of women and 37% of men had the results of bone density below the norm.

[Effect of lead on thyroid function]. / Wplyw olowiu na funkcje tarczycy.

Lead in organic and inorganic compounds is a health risk factor leading after high-grade exposure to poisoning. It can accumulate in the organism and exert toxic effects, especially on the haemopoietic system and nervous system. Its action includes damage to cell membranes and disorders of the oxidoreductive processes in the cells. Hypothyroidism occurring in subjects with occupational exposure to lead may evidence a negative effect of the element on thyroid function.

[Clinical trial of the treatment of rheumatoid arthritis with TFX (thymus factor X)]. / Próba leczenia reumatoidalnego zapalenia stawów preparatem TFX (Thymus factor X).

The results of rheumatoid arthritis treatment with the preparation TFX (extract of calf thymus) are reported. The drug was given to 11 patients with intense inflammatory process treated previously in typical fashion without evident improvement and in whom immunological studies demonstrated disturbances of cell-mediated and humoral response. The duration of treatment and observation was 6 months. In 9 patients clinical improvement was achieved. We observed no correlation between clinical improvement and immunological indices besides statistically significant changes of skin tests. The results (assessment of health state, laboratory investigations) encourage to TFX use in the treatment of rheumatoid arthritis.

[Possibility of using TFX (thymus factor X) in the treatment of systemic lupus erythematosus]. / Mozliwosc zastosowania preparatu TFX (thymus factor X) w leczeniu tocznia ukladowego.

A case of a 32-year female patient with the systemic lupus erythematosus is presented. The patient was treated with prednisone in a daily dose of 40-60 mg. Due to the exacerbations of the symptoms and advanced renal disorders, the patient was given TFX together with corticotherapy. Thymus factor X is an extract of real thymus of immunorecorrective properties. It specifically acts on the lymphatic system, especially disordered mechanisms of both cellular and humoral immunity. Thymus factor X was given in the dose of 10 mg (one ampoule) i.m. for the three first months followed by one ampoule every three days for the next three months. The patient is given one ampoule of TFX once a week since the 6th months of therapy. Diminishment of the symptoms was observed. The patient is in remission since a one-year follow-up period. It was also possible to reduce the dose of prednisone to 15 mg a day. The patient is controlled every 3 months. Partial normalization of renal functioning and immunological mechanisms are seen. A decrease in antinuclear antibodies and immunoglobulins, normalization in complement components, an increase in T-cells percentage and conversion of the delayed skin reaction are noted. The authors conclude that TFX may be helpful in the treatment of the autoimmunological diseases, including the systemic lupus erythematosus.

[Studies of the effect of environmental factors on the visual system (based on the examination of workers at a precision instrument factory)]. / Wplyw czynników srodowiskowykh na stan ukLadu wzrokowego (na podstawie badan przeprowadzonych u pracowników zakladów wytwórczych aparatury precyzyjnej.

The studies involved 254 workers of a Precise Devices Plant. The impact of working conditions (chemical pollutants and lighting) on the sight organ was examined. In the test group a considerable percentage (29.5%) of chronic conjunctivitis was found. The disease results from a long-lasting exposure to dusts of various origin, as well as from improper lighting. The posttraumatic and post-inflammatory impairments of the sight organ, diagnosed by ophthalmological examinations, were not of occupational origin.