ABSTRACT
Once the inadvertent infiltration of Adriamycin occurs, it is recommended to immediately treat the problem. This has been accomplished by wide excision and meshed split thickness skin grafting for resurfacing of the defect. Obtaining a healed wound alleviates the stiffness from lack of motion or ruptured tendons. Pain from the open ulcer, which is prone to infection in the immunosuppressed patient, is lessened. An analogy between pit viper envenomization and Adriamycin infiltration is discussed.
Subject(s)
Cellulitis/chemically induced , Doxorubicin/adverse effects , Skin Ulcer/chemically induced , Adenocarcinoma/drug therapy , Breast Neoplasms/drug therapy , Child , Female , Humans , Leukemia/drug therapy , Male , Middle Aged , Skin TransplantationABSTRACT
In a series of patients who underwent closed rupture of fibrous capsules surrounding mammary prostheses, 3 patients developed hematomas or rupture of the implant, with or without infection. These complications and their management are discussed. Closed capsulotomy is a valuable procedure, simple to apply and easy to learn, but it is not devoid of complications.
Subject(s)
Breast/surgery , Postoperative Complications/surgery , Surgery, Plastic , Adult , Breast Diseases/etiology , Female , Hematoma/surgery , Humans , Prostheses and Implants/adverse effects , Silicones/adverse effectsABSTRACT
A 32-year-old morbidly obese woman had bilateral subclavian artery embolism. After embolectomy, a right heart catheterization showed a patent foramen ovale and a right-to-left shunt. Pulmonary angiography revealed multiple pulmonary emboli. Bilateral lower extremity venography demonstrated left ileofemoral thrombi as the probable source. The patient was successfully treated with an inferior vena caval umbrella and anticoagulant drugs.
