Robust cortical encoding of 3D tongue shape during feeding in macaques.

Dexterous tongue deformation underlies eating, drinking, and speaking. The orofacial sensorimotor cortex has been implicated in the control of coordinated tongue kinematics, but little is known about how the brain encodes-and ultimately drives-the tongue's 3D, soft-body deformation. Here we combine a biplanar x-ray video technology, multi-electrode cortical recordings, and machine-learning-based decoding to explore the cortical representation of lingual deformation. We trained long short-term memory (LSTM) neural networks to decode various aspects of intraoral tongue deformation from cortical activity during feeding in male Rhesus monkeys. We show that both lingual movements and complex lingual shapes across a range of feeding behaviors could be decoded with high accuracy, and that the distribution of deformation-related information across cortical regions was consistent with previous studies of the arm and hand.

Loss of oral sensation impairs feeding performance and consistency of tongue-jaw coordination.

BACKGROUND: Individuals with impaired oral sensation report difficulty chewing, but little is known about the underlying changes to tongue and jaw kinematics. Methodological challenges impede the measurement of 3D tongue movement and its relationship to the gape cycle. OBJECTIVE: The aim of this study was to quantify the impact of loss of oral somatosensation on feeding performance, 3D tongue kinematics and tongue-jaw coordination. METHODOLOGY: XROMM (X-ray Reconstruction of Moving Morphology) was used to quantify 3D tongue and jaw kinematics during feeding in three rhesus macaques (Macaca mulatta) before and after an oral tactile nerve block. Feeding performance was measured using feeding sequence duration, number of manipulation cycles and swallow frequency. Coordination was measured using event- and correlation-based metrics of jaw pitch, anterior tongue length, width and roll. RESULTS: In the absence of tactile sensation to the tongue and other oral structures, feeding performance decreased, and the fast open phase of the gape cycle became significantly longer, relative to the other phases (p < .05). The tongue made similar shapes in both the control and nerve block conditions, but the pattern of tongue-jaw coordination became significantly more variable after the block (p < .05). CONCLUSION: Disruption of oral somatosensation impacts feeding performance by introducing variability into the typically tight pattern of tongue-jaw coordination.