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J Clin Microbiol ; 49(7): 2685-7, 2011 Jul.
Article in English | MEDLINE | ID: mdl-21562111

ABSTRACT

This study shows the benefit of spoligotyping coupled to mycobacterial interspersed repetitive-unit (MIRU) typing to pinpoint circulating Mycobacterium tuberculosis genotypes in Guadeloupe, Martinique, and French Guiana. We hereby propose reduced 4-locus and 6-locus subsets for LAM and Haarlem lineage strains that predominate in South America and the Caribbean, retaining 99.35% and 99.64% of the total discriminatory power of the 12-locus scheme, respectively.


Subject(s)
Molecular Typing , Mycobacterium tuberculosis/classification , Mycobacterium tuberculosis/genetics , Tuberculosis/epidemiology , Tuberculosis/microbiology , Adolescent , Adult , Aged , Aged, 80 and over , DNA, Bacterial/genetics , French Guiana/epidemiology , Genotype , Guadeloupe/epidemiology , Humans , Male , Martinique/epidemiology , Middle Aged , Molecular Epidemiology/methods , Mycobacterium tuberculosis/isolation & purification , Young Adult
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