ABSTRACT
The purpose of this study was to investigate the phylogenetic relationship of the Juquitiba virus (JUQV) carried by Oligoryzomys nigripes in endemic and non-endemic areas of Brazil. Wild rodents infected with the Juquitiba virus (JUQV) were sampled from a non-Hantavirus Cardiopulmonary Syndrome endemic area in Brazil. Three strains from O. nigripes were identified by the sequencing of the complete S segment and compared to previous studies of JUQV available in GenBank. The phylogenetic analysis of the complete S segment revealed two distinct clades; the first clade was composed of the JUQV from two non-endemic areas in Brazil and the second clade contained JUQV strains from Argentina, Paraguay and other Brazilian endemic areas.
Subject(s)
Arvicolinae/virology , Orthohantavirus/classification , Viral Proteins/genetics , Amino Acid Sequence , Animals , Bayes Theorem , Brazil , Orthohantavirus/genetics , Molecular Sequence Data , Phylogeny , Sequence AlignmentABSTRACT
We associated Laguna Negra virus with hantavirus pulmonary syndrome in Mato Grosso State, Brazil, and a previously unidentified potential host, the Calomys callidus rodent. Genetic testing revealed homologous sequencing in specimens from 20 humans and 8 mice. Further epidemiologic studies may lead to control of HPS in Mato Grosso State.
Subject(s)
Hantavirus Pulmonary Syndrome/veterinary , Orthohantavirus/genetics , Rodent Diseases/virology , Animals , Arvicolinae , Bayes Theorem , Brazil/epidemiology , Genetic Variation , Orthohantavirus/classification , Hantavirus Pulmonary Syndrome/epidemiology , Hantavirus Pulmonary Syndrome/virology , Humans , Likelihood Functions , Mice , Multilocus Sequence Typing , Nucleocapsid Proteins/genetics , Phylogeny , Rodent Diseases/epidemiologyABSTRACT
To study the dynamics of wild rodent populations and identify potential hosts for hantavirus, we conducted an eco-epidemiologic study in Campo Novo do Parecis, Mato Grosso State, Brazil. We detected and genetically characterized Castelo dos Sonhos virus found in a species of pygmy rice rat (Oligoryzomys utiaritensis).
