[Chemical anabiosis by aldehydes and protection of organs and tissues from ischemic damage]. / Khimicheskii anabioz al'degidami, zashchita organov i tkanei ot ishemicheskikh povrezhdenii.

The article is devoted to the medical biological problem that is the impact of endogenic aldehyde (methylenglucol) on tissue structures with the purpose of defending them from ischemic damage by reverse reduction of intensity of metabolic reactions, which is conditioned by reverse inhibition of the oxidation processes phosphorylation connected with reduction of losses and adenosine 5-triphosphate forming. It is ascertained that until methylenglucol in the ischemic tissue of concrete organ hasn't reduced to a certain critical level there is still an opportunity to reanimate this organ.

[Reparative osteogenesis in bone fractures under the experimental and clinical influence of exposure in the early trauma period to a UHF electrical field]. / Reparativnyi osteogenez pri perelome kostei pod vliianiem vozdeistviia v rannem periode travmy élektricheskogo polia UVCh v éksperimente i klinike.

A 4-mm fracture-induced radius defect in rabbits was exposed to UHF electric field (40, 68 MHz, 20 W). The exposure promoted reparative osteogenesis though consolidation of the fragments followed the pattern of periosteal osteogenesis. Clinical data agreed with the above experimental findings.

[The essence of osteoid osteomas and osteoblastomas]. / O sushchnosti osteoidnykh osteom i osteoblastom.

178 cases of osteoid osteomas and osteoblastomas collected during 35 years were studied morphologically and roentgenologically (angiography--28 cases). Clear-cut differences between these two lesions were revealed. The differences concerned: 1) the character of the border with the surrounding bone tissue; 2) the morphology of bone structures being chaotic in the osteoblastoma; 3) intensity of proliferation in the osteogenic tissue; 4) differences in the angiographic data. According to the author's opinion osteoblastoma is a blastomogenic process with destructive growth and intensive proliferation. Classical osteoid osteoma does not possess these properties and is the result of dysontogenetic development of the intraosseous vascular system.

[Destructive and reparative processes after UHF and cryo-effect on bone regeneration in dogs]. / Destruktivnye i reparativnye protsessy posle SVCh i kriovozdeistviia na kostnyi regenerat sobak.

The experiment was carried out on the lower jaw of mongrel dogs. It included 36 observations on the basis of the morphological method. The aim is to study the effectiveness of the effect of cold and the combination of the UHF radiation on the proliferative reaction of cells of the lower jaw. It was proved that under the influence of cold the skeletogenic tissue undergoes changes. The combination of cold with UHF radiation cause less destructive cold effects on the bone tissue away from the injury of resorption. Hence the effect of cold on the proliferating tissue causing its necrosis proves the possibility of its use in removal of tumours, substituting wide caving around them by more protective intervention: the combination of carving of tumour with the cryodestruction of tissue around it. In such a combination the reparative processes become more effective, which enables us to recommend them for clinical use for curing benign tumour.

[Development and differentiation of bone marrow mechanocytes]. / K voprosu ob izuchenii razvitiia i differentsirovki mekhanotsitov kostnogo mozga.

Morphological studies in the model with the complete destruction of bone marrow in the diaphysis of the tubular bone have revealed the process of stromal elements regeneration. Within the first 24 hours after the trauma insignificant accumulations of fibroblast-like cells in the lumen of some vascular channels have been observed in cell-free cortical plates. In two days spheric cells with a large dense nucleus were detected in tissue-free bone-marrow diaphysis cavity. This fact seems indicative of the viability of the vascular channel cells. This was manifested in the regained tinctorial and biological properties (i.e. the ability to proliferate). The recovery of these properties are likely to be related to vessel pericytes in the microcirculatory net of the vascular channels.

[Histogenesis of skeletogenic tissue in bone regeneration during distraction]. / K gistogeneze skeletogennoi tkani pri regeneratsii kosti v usloviiakh distraktsii.

Light and electron microscopy were employed to study the histogenesis of the skeletogenous tissue during stable distraction osteosynthesis according to G. A. Ilizarov. Osteosynthesis proceeded on the basis of the invariably existing fibrillar connective tissue growth plate situated in the medium part of the distraction regenerate. Osteogenesis was continuously accompanied by angiogenesis. Preservation of the connective tissue plate is accounted for by the stimulating influence of distraction on fibrillogenesis. The authors suggest the common character of the histogenesis of the vascular and bone tissues in the connective tissue blastema of the interfragmental distraction regenerate.