Biomechanical Testing and Histologic Examination of Intradermal Skin Closure in Dogs Using Barbed Suture Device and Non-Barbed Monofilament Suture.

OBJECTIVE: To compare the biomechanical strength and histologic features of 3-0 Glycomer™ 631 barbed suture (V-LOC™ 90 Absorbable Wound Closure Device, Covidien, Mansfield, MA) to non-barbed 3-0 Glycomer™ 631 suture (Biosyn™, Covidien) for intradermal skin wound closure in the dog. STUDY DESIGN: Randomized, factorial, in vivo. ANIMALS: Eighteen purpose-bred, mature male, and female hound dogs. METHODS: Eighteen adult hound dogs were randomly assigned to 1 of 3 groups designated by postoperative day of assessment. Six skin incisions were made along the dorsum in the thoracolumbar region of each dog with an equal number (n=3) randomly assigned to closure with barbed or non-barbed suture. Six dogs were euthanatized on postoperative days 3, 10, and 14, respectively. Two additional incisions were made on each dog after euthanasia for baseline data (Day 0). The skin incision specimens were harvested for biomechanical testing and histologic evaluation. RESULTS: Non-barbed closure had significantly higher maximum load at failure (P<.001) and stiffness (P<.001) than barbed closure regardless of day. The average tissue reaction score was significantly higher for barbed closure (P=.008), regardless of day. Suturing time for barbed closures was significantly shorter. There was no significant difference in frequency of complications between closures. CONCLUSION: Barbed Glycomer™ 631 closures had a significantly lower maximum load at failure and stiffness, and higher average tissue reaction scores, but showed no difference in short term outcome for intradermal closure of dorsally located skin incisions in dogs.

Cementless total hip replacement in 20 juveniles using BFX™ arthroplasty.

OBJECTIVE: To describe outcome after a minimum of 1 year for total hip replacement (THR) using BioMedtrix BFX™ biologic fixation implants in skeletally immature dogs (6-10 months of age). STUDY DESIGN: Case series. ANIMALS: Dogs (n = 20). METHODS: Medical records (November 2007-June 2010) of 20 dogs, 6-10 months old that had cementless THR were reviewed. Preoperative, immediate, 6-week and >1-year postoperative radiographs were compared. Clinical examination was performed at 6 weeks and >1 year postoperatively. Owner questionnaire was obtained at final follow-up. RESULTS: Cementless THR using BFX™ implants was performed because of debilitating coxofemoral pain, resulting from canine hip dysplasia, after unsatisfactory outcome with medical management. Radiographs taken immediately, 6 weeks and at a mean of 29.8 months (range, 12-48 months) postoperatively revealed satisfactory implant positioning and stability. Significant change in measured cranial-caudal femoral stem fill and level (P < .001 and P = .006, respectively) were recorded at 6 weeks postoperatively without clinical significance. No further change in stem positioning occurred. Acetabular cup orientation remained unchanged throughout follow-up. Complications requiring further surgical intervention were not encountered. One minor superficial infection was recorded and treated. Lameness and pain on manipulation of the affected hip had greatly improved in all dogs by 6 weeks postoperatively. CONCLUSION: Cementless THR can safely be performed in skeletally immature dogs, providing satisfactory return to normal joint function and implant survivability for at least a mean of 29.8 months.