ABSTRACT
We describe the evolution of cardiac magnetic resonance imaging findings in 16 patients, aged 12-17 years, with myopericarditis after the second dose of the Pfizer mRNA coronavirus disease 2019 vaccine. Although all patients showed rapid clinical improvement, many had persistent cardiac magnetic resonance imaging findings at 3- to 8-month follow-up.
Subject(s)
COVID-19 , Myocarditis , Pericarditis , Adolescent , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Humans , Magnetic Resonance Imaging , Myocarditis/diagnostic imaging , Myocarditis/etiology , Pericarditis/diagnostic imaging , Pericarditis/etiology , RNA, Messenger , Vaccines, Synthetic , mRNA VaccinesABSTRACT
Reports have emerged of myocarditis and pericarditis predominantly after the second dose of the coronavirus disease messenger ribonucleic acid vaccine. We describe 13 patients aged 12-17 years who presented with chest pain within 1 week after their second dose of the Pfizer vaccine and were found to have elevated serum troponin levels and evidence of myopericarditis.
Subject(s)
COVID-19 Vaccines/adverse effects , COVID-19/prevention & control , Myocarditis/etiology , Pericarditis/etiology , SARS-CoV-2/immunology , Vaccination/adverse effects , Vaccines, Synthetic/adverse effects , Adolescent , BNT162 Vaccine , COVID-19/epidemiology , Child , Female , Humans , Incidence , Male , Myocarditis/epidemiology , Pandemics , Pericarditis/epidemiology , Retrospective Studies , Washington/epidemiology , mRNA VaccinesABSTRACT
Paediatric heart transplantation has evolved over the last 3 decades. The research group, Pediatric Heart Transplant Study, has been in step with that evolution over the nearly 20 years of its existence by utilising its registry to contribute a wealth of clinical research to the field. The highlights of its studies will be presented in this review.