1.
Biol Psychiatry
; 32(7): 617-20, 1992 Oct 01.
Article
in English
| MEDLINE
| ID: mdl-1450288
Subject(s)
Arousal , Attention , Orientation , Schizophrenia/diagnosis , Schizophrenic Psychology , Visual Perception , Arousal/drug effects , Attention/drug effects , Clozapine/therapeutic use , Haloperidol/therapeutic use , Humans , Orientation/drug effects , Psychiatric Status Rating Scales , Psychomotor Performance/drug effects , Reaction Time/drug effects , Schizophrenia/drug therapy , Visual Perception/drug effects
2.
Neuropsychobiology
; 25(2): 99-101, 1992.
Article
in English
| MEDLINE
| ID: mdl-1625783
ABSTRACT
Electroretinographic (ERG) measurements were performed in 9 schizophrenic patients and in 13 control subjects. The measurements of schizophrenic patients as a group did not differ from those of normals. However, 6 schizophrenic patients who had a past history of sun gazing showed a decrease in retinal responsiveness under conditions of light adaptation. These results suggest that a subgroup of schizophrenic patients, who show deviant light-related behavior, have abnormal ERG. We postulate that an abnormality in retinal dopaminergic neurons, which are known to reduce light responsiveness of horizontal and ganglion cells, is the underlying pathophysiology of this clinical finding.