ABSTRACT
OBJECTIVES: Relationships among cognitive and motivational factors in predicting medical help-seeking for Alzheimer's disease (AD) symptoms were tested. METHOD: Community residents awaiting jury service (N = 280) completed questionnaires, including responses to a vignette depicting prototypical early symptoms of AD in a hypothetical mother. Cognitive responses to the vignette included AD symptom identification and AD attribution. Affective-motivational responses to vignettes were symptom impact and behavior appraisals. General knowledge of AD was assessed. Intention to seek medical help was the dependent variable. RESULTS: The impact and identification of AD symptoms, appraisals of risk, and attribution of the scenario to AD were modest, yet all contributed to prediction of medical-help-seeking intentions. The best fitting model had distinct but interrelated cognitive and motivational paths explaining 49% of the variability in medical help-seeking. Motivational variables had particularly important direct and indirect effects on help-seeking. DISCUSSION: Findings are interpreted as evidence of the importance of motivational as well as cognitive aspects of perceptions of illness behavior in another person. The substantial impact of the tested variables on the desired outcome of medical help-seeking may suggest options for public health efforts to enhance early medical help-seeking for AD that sets the stage for early intervention.
Subject(s)
Alzheimer Disease/psychology , Cognition Disorders/psychology , Health Knowledge, Attitudes, Practice , Models, Psychological , Patient Acceptance of Health Care/psychology , Adolescent , Adult , Aged , Alzheimer Disease/therapy , Cognition Disorders/therapy , Female , Humans , Male , Middle Aged , Motivation/physiology , Young AdultABSTRACT
The relative sensitivity of mismatch negativity (MMN) amplitude to small changes in temporal (i.e. timing) deviance of an ongoing stimulus train was investigated. MMN was measured at Fz in response to 3.75-15% decrements of inter-stimulus interval from a 400 ms standard with a deviant probability of 1/15. This parameter space represents the smallest degree of deviance and the narrowest range of variation that has been tested in the context of MMN sensitivity to temporal variables. Waveform amplitude was found to significantly increase with degree of temporal deviance even within this relatively narrow parameter space. This finding is consistent with the view that the MMN corresponds to pre-attentive neural activity that subsequently allows the conscious perception of time during temporal discrimination tasks.
