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1.
Small bowel perforation and fatal peritonitis following a fall in a 21-month-old child.
Davison, Andrew M; Lazda, Edgar J.
Forensic Sci Med Pathol ; 4(4): 250-4, 2008.
Article in English | MEDLINE | ID: mdl-19291447

ABSTRACT

The authors report a case of fatal peritonitis due to small bowel perforation in a 21-month-old female child. Necropsy excluded natural disease and a thorough Coronial investigation concluded that an accidental fall onto a "doorstop" caused the bowel injury. The investigative findings are presented; the discussion address issues of diagnosis and causation/mechanism of injury.


Subject(s)
Accidental Falls , Intestinal Perforation/pathology , Intestine, Small/injuries , Peritonitis/pathology , Wounds, Nonpenetrating/complications , Abdominal Injuries/complications , Female , Forensic Pathology , Humans , Infant , Intestinal Perforation/etiology , Intestine, Small/pathology , Peritonitis/etiology , Vomiting/etiology
2.
Early fetal death associated with compound heterozygosity for Noonan syndrome-causative PTPN11 mutations.
Becker, Kristin; Hughes, Helen; Howard, Karol; Armstrong, Maggie; Roberts, Devender; Lazda, Edgar J; Short, John P; Shaw, Adam; Patton, Michael A; Tartaglia, Marco.
Am J Med Genet A ; 143A(11): 1249-52, 2007 Jun 01.
Article in English | MEDLINE | ID: mdl-17497712

Subject(s)
Fetal Death/enzymology , Fetal Death/genetics , Heterozygote , Intracellular Signaling Peptides and Proteins/genetics , Mutation/genetics , Noonan Syndrome/enzymology , Noonan Syndrome/genetics , Protein Tyrosine Phosphatases/genetics , Adult , Child, Preschool , Female , Fetus/enzymology , Gestational Age , Humans , Male , Pregnancy , Protein Tyrosine Phosphatase, Non-Receptor Type 11 , Ultrasonography, Prenatal
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