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1.
Nat Prod Res ; 33(5): 695-700, 2019 Mar.
Article in English | MEDLINE | ID: mdl-29212359

ABSTRACT

One new and three known compounds were isolated from the ethanol extract of Psychotria prainii aerial parts. By means of spectroscopic methods, their structures were elucidated to be deacetylasperulosidic acid 6-ethyl ether (1), asperulosidic acid (2), asperuloside (3) and obtucarbamates C (4). The isolated compounds were evaluated for their inhibitory effect on NO production in LPS-stimulated RAW264.7 cells. Among them, compounds 2 and 4 exhibited strong effect with the IC50 values of 5.75 ± 0.85 and 6.92 ± 0.43 µM, respectively. This is the first report for the chemical composition and biological activity of P. prainii.


Subject(s)
Anti-Inflammatory Agents/pharmacology , Carbamates/pharmacology , Glycosides/pharmacology , Psychotria/chemistry , Animals , Anti-Inflammatory Agents/isolation & purification , Carbamates/isolation & purification , Cyclopentane Monoterpenes , Glucosides , Glycosides/isolation & purification , Mice , Molecular Structure , Phytochemicals/isolation & purification , Phytochemicals/pharmacology , Plant Components, Aerial/chemistry , Plant Extracts/chemistry , Pyrans , RAW 264.7 Cells , Vietnam
2.
Article in English | WPRIM (Western Pacific) | ID: wpr-77744

ABSTRACT

The first study on chemical constituents and biological activities of Clausena lansium (Lour.) Skeels (Rutaceae) growing in Vietnam has been done. Phytochemical investigation of n-hexane extract led to the isolation of five compounds: dihydroindicolactone (1), 8-geranyloxy psoralen (2), imperatorin (3), heraclenol (4) and indicolactone (5), in which this is the first report on the presence of dihydroindicolactone (1). Their structures were elucidated based on LC/MS/NMR hyphenated techniques as well as comparison with those of literature data. The n-hexane extract and its subfractions, ethanol 95% extract and several isolated compounds were evaluated for antifungal activity.


Subject(s)
Clausena , Ethanol , Ficusin , Vietnam
3.
Environ Monit Assess ; 186(2): 845-58, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24114277

ABSTRACT

In this study, we focused on water quality in an urban canal and the Mekong River in the city of Can Tho, a central municipality of the Mekong Delta region, southern Vietnam. Water temperature, pH, electrical conductivity, BOD5, CODCr, Na(+), Cl(-), NH4 (+)-N, SO4 (2-)-S, NO3 (-)-N, and NO2 (-)-N for both canal and river, and tide level of the urban canal, were monitored once per month from May 2010 to April 2012. The urban canal is subject to severe anthropogenic contamination, owing to poor sewage treatment. In general, water quality in the canal exhibited strong tidal variation, poorer at lower tides and better at higher tides. Some anomalies were observed, with degraded water quality under some high-tide conditions. These were associated with flow from the upstream residential area. Therefore, it was concluded that water quality in the urban canal changed with a balance between dilution effects and extent of contaminant supply, both driven by tidal fluctuations in the Mekong River.


Subject(s)
Cities/statistics & numerical data , Environmental Monitoring , Rivers/chemistry , Water Pollutants/analysis , Water Supply/statistics & numerical data , Humans , Vietnam
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