1.
Org Lett
; 9(17): 3401-4, 2007 Aug 16.
Article
in English
| MEDLINE
| ID: mdl-17658843
ABSTRACT
Dynamic kinetic resolution (DKR) of a series of sterically hindered allylic alcohols has been conducted with Candida antarctica lipase B (CALB) and ruthenium catalyst 1. The optically pure allylic acetates obtained were subjected to oxidative cleavage to give the corresponding acylated acyloins in high yields without loss of chiral information.