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1.
Rev Esp Med Nucl ; 21(1): 17-23, 2002 Feb.
Article in Spanish | MEDLINE | ID: mdl-11820997

ABSTRACT

A pilot study was carried out in the Nuclear Medicine Department of the National Institute of Oncology and Radiobiology to learn the diagnostic efficacy of the 99mTc-HMPAO scintigraphy in the detection of cutaneous melanoma, distant and local metastases, in patients with a confirmed histological diagnosis. The planar and/or SPECT scintigraphy was performed in 17 patients and revealed 90% sensitivity for the detection of the disease. We calculated the tumor/background index in all the images obtained and found a value greater than 1 in every case. Thus, we can affirm that the 99mTc-HMPAO accumulation in tumors was higher than the background in all cases. We recommend that this procedure be considered in the follow up of these patients as a new diagnostic method which is very useful in the determination of the patient stage and prognostic evaluation.


Subject(s)
Melanoma/diagnostic imaging , Neoplasm Metastasis/diagnostic imaging , Neoplasm Recurrence, Local/diagnostic imaging , Radiopharmaceuticals , Skin Neoplasms/diagnostic imaging , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon , Adult , Aged , Aged, 80 and over , False Negative Reactions , False Positive Reactions , Female , Follow-Up Studies , Humans , Male , Melanoma/pathology , Melanoma/surgery , Middle Aged , Pilot Projects , Sensitivity and Specificity , Skin Neoplasms/pathology , Skin Neoplasms/surgery
2.
Rev. esp. med. nucl. (Ed. impr.) ; 21(1): 17-23, ene. 2002.
Article in Es | IBECS | ID: ibc-11202

ABSTRACT

Se realiza un estudio piloto para comprobar la eficacia diagnóstica de la gammagrafía con 99mTcHMPAO en la detección del melanoma cutáneo, sus metástasis y recidivas en pacientes del INOR con diagnóstico histológico confirmado. Las gammagrafías planas y/o SPECT realizadas con este radiofármaco a 17 pacientes aquejados de la enfermedad demostraron una sensibilidad del 90 por ciento para esta serie. Se calculó el Índice Tumor/Fondo en cada imagen obtenida, encontrándose que en todos los casos el mismo resultaba mayor que 1, por lo que puede afirmarse que la acumulación del 99mTc-HMPAO en los tumores fue mayor que en el fondo radiactivo en todos los casos. Se recomienda tener en cuenta este proceder diagnóstico en el seguimiento evolutivo de estos pacientes ya que puede emplearse como un nuevo método de diagnóstico muy útil en el estadiamiento y evaluación pronóstica de estos pacientes (AU)


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Subject(s)
Middle Aged , Adult , Aged, 80 and over , Aged , Male , Female , Humans , Tomography, Emission-Computed, Single-Photon , Sensitivity and Specificity , Radiopharmaceuticals , Technetium Tc 99m Exametazime , Melanoma , Pilot Projects , False Positive Reactions , False Negative Reactions , Follow-Up Studies , Skin Neoplasms , Neoplasm Metastasis , Neoplasm Recurrence, Local
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