ABSTRACT
Our study included 25 subjects, ten with normal intestinal habits and 15 with colonic diverticulosis. Data was collected from X-rays of gastrointestinal transit times and from intraluminal pressures in the sigmoid and rectum, using electromanometry. A comparison of the results led to the following conclusions: 1) transit times to the cecum were essentially similar in both the control subjects and patients with diverticulosis; 2) the barium contrast arrived twice as fast in the proximal sigmoid of patients with diverticulosis compared to the control group. Therefore, there is an increase in the transit between the cecum and sigmoid in individuals with diverticulosis of the colon; 3) the mean of the total time of gastrointestinal emptying is similar in both groups; 4) under unstimulated conditions, the electromanometric study of the sigmoid and rectum was similar in both groups; 5) the sigmoid region in patients with diverticulosis has a modulating transit capacity delaying it. This modulation was not reflected in the electromanometric study as an increase in motor activity.
Subject(s)
Diverticulum, Colon/physiopathology , Gastrointestinal Motility , Adult , Aged , Barium Sulfate , Diverticulum, Colon/diagnosis , Enema , Female , Gastric Emptying , Humans , Intestines/diagnostic imaging , Male , Manometry , Middle Aged , Pressure , RadiographyABSTRACT
Foram estudados 25 individuos, dez com habito intestinal normal e 15 com diverticulose colonica. Os parametros analisados foram o tempo de transito em radiografias gastrointestinais e a analise das pressoes intraluminais do reto sigmoide por eletromanometria. A comparacao dos resultados em ambos os grupos permitiu as seguintes conclusoes: 1) o tempo de transito ate o ceco foi semelhante nos dois grupos; 2) nos pacientes com diverticulose, o contraste baritado chegou ao sigmoide proximal na metade do tempo dos normais; 3) a media do tempo total de esvaziamento gastrointestinal foi similar nos dois grupos; 4) o estudo eletromanometrico do reto sigmoide foi similar nos dois grupos, em condicoes sem estimulacao; 5) a regiao do sigmoide, em pacientes com diverticulose, tem um retardo na capacidade moduladora do transito Entretanto, no estudo eletromanometrico nao se detectou aumento da atividade motora
Subject(s)
Adult , Middle Aged , Humans , Male , Female , Diverticulosis, Colonic , Gastrointestinal MotilitySubject(s)
Adult , Middle Aged , Humans , Male , Female , Endoscopy , Gastrointestinal Hemorrhage , Liver Cirrhosis , Schistosomiasis , Hypertension, PortalABSTRACT
Three patients with chronic active hepatitis received Colchicine therapy, as an antifibrotic drug. The effect of this drug is analysed biochemically (serum albumin, total serum billirubin and amino-transferase aspartate) and histologically before and after colchicine therapy. Biochemical improvement was observed. No histological change was noted.