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1.
Tumour immunology: NLRC3 inhibits mTOR in colorectal cancer.
Leavy, Olive.
Nat Rev Immunol ; 17(2): 79, 2017 02.
Article in English | MEDLINE | ID: mdl-28044056

Subject(s)
Colorectal Neoplasms , TOR Serine-Threonine Kinases , Humans , Intercellular Signaling Peptides and Proteins
2.
T cells: A tissue checkpoint for TH2s.
Leavy, Olive.
Nat Rev Immunol ; 16(12): 717, 2016 11 25.
Article in English | MEDLINE | ID: mdl-27885277

Subject(s)
Th1 Cells , Th2 Cells , Humans
3.
Regulatory T CELLS: Suppressing antibody production.
Leavy, Olive.
Nat Rev Immunol ; 16(11): 659, 2016 10 26.
Article in English | MEDLINE | ID: mdl-27782146

Subject(s)
Antibody Formation , T-Lymphocytes, Regulatory/immunology , Autoantibodies/immunology , Humans
4.
Innate immune cells: A Morrbid way of stayin' alive.
Leavy, Olive.
Nat Rev Immunol ; 16(10): 595, 2016 10.
Article in English | MEDLINE | ID: mdl-27616588
5.
B cells: Genomic reorganization in germinal centres.
Leavy, Olive.
Nat Rev Immunol ; 16(10): 594-5, 2016 09 27.
Article in English | MEDLINE | ID: mdl-27670367

Subject(s)
B-Lymphocytes , Germinal Center , Genomics , Humans
6.
T Cell responses: Defective mitochondria disrupt CD8(+) T cells.
Leavy, Olive.
Nat Rev Immunol ; 16(9): 534-5, 2016 08 25.
Article in English | MEDLINE | ID: mdl-27558410

Subject(s)
CD4-Positive T-Lymphocytes/immunology , CD8-Positive T-Lymphocytes/immunology , Humans , Lymphocyte Activation , Mitochondria
7.
Asthma and allergy: Old McDonald had a farm (but no asthma)!
Leavy, Olive.
Nat Rev Immunol ; 16(9): 535, 2016 08 25.
Article in English | MEDLINE | ID: mdl-27558411

Subject(s)
Asthma , Farms , Humans , Hypersensitivity
8.
Mucosal immunology: Glial cells support ILC3s and gut defence.
Leavy, Olive.
Nat Rev Immunol ; 16(8): 466-7, 2016 07 27.
Article in English | MEDLINE | ID: mdl-27461150

Subject(s)
Interleukins , Lymphocytes , Humans , Intestinal Mucosa , Neuroglia
9.
Macrophages: Memories of the dead give strength.
Leavy, Olive.
Nat Rev Immunol ; 16(8): 464-5, 2016 08.
Article in English | MEDLINE | ID: mdl-27374638

Subject(s)
Macrophages , Memory , Humans
10.
Antiviral immunity: CD4(+) T cells open the door for antibodies.
Leavy, Olive.
Nat Rev Immunol ; 16(7): 404-5, 2016 07.
Article in English | MEDLINE | ID: mdl-27291963

Subject(s)
Antiviral Agents , CD4-Positive T-Lymphocytes/immunology , Antibodies , Humans
11.
Cardiovascular disease: Dissolving cholesterol to unclog arteries.
Leavy, Olive.
Nat Rev Drug Discov ; 15(5): 308-9, 2016 05 03.
Article in English | MEDLINE | ID: mdl-27139992

Subject(s)
Arteries , Cholesterol , Cardiovascular Diseases , Humans
12.
Innate immunity: Sensing broken antibody.
Leavy, Olive.
Nat Rev Immunol ; 16(6): 336-7, 2016 06.
Article in English | MEDLINE | ID: mdl-27180813

Subject(s)
Antibodies , Immunity, Innate , Humans
13.
Neonatal immunity: Maternal IgG promotes intestinal homeostasis.
Leavy, Olive.
Nat Rev Immunol ; 16(6): 335, 2016 05 27.
Article in English | MEDLINE | ID: mdl-27231048

Subject(s)
Intestines , Receptors, Fc , Animals, Newborn , Homeostasis , Humans , Immunoglobulin G
14.
Macrophages: Dissolving cholesterol to unclog arteries.
Leavy, Olive.
Nat Rev Immunol ; 16(5): 274-5, 2016 04 28.
Article in English | MEDLINE | ID: mdl-27121648

Subject(s)
Arteries , Cholesterol , Blood Cell Count , Humans , Macrophages
15.
T cell responses: Metabolic pathways take sides.
Leavy, Olive.
Nat Rev Immunol ; 16(5): 276-7, 2016 04 28.
Article in English | MEDLINE | ID: mdl-27121650

Subject(s)
Lymphocyte Activation , T-Lymphocytes/immunology , Humans , Metabolic Networks and Pathways
16.
Immune memory: T-box tuning for TRM cell fate.
Leavy, Olive.
Nat Rev Immunol ; 16(2): 71, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26781937

Subject(s)
CD8-Positive T-Lymphocytes/immunology , Immunologic Memory/immunology , Interleukin-15/immunology , T-Box Domain Proteins/immunology , Transforming Growth Factor beta/immunology , Animals
17.
Immune memory: Sequential evolution of B cell memory.
Leavy, Olive.
Nat Rev Immunol ; 16(2): 72-3, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26806486

Subject(s)
B-Lymphocyte Subsets/cytology , B-Lymphocytes/cytology , Cell Differentiation/immunology , Germinal Center/immunology , Immunologic Memory/immunology , Plasma Cells/cytology , Animals
18.
Regulatory T cells: Developing diversity.
Leavy, Olive.
Nat Rev Immunol ; 16(1): 2-3, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26655624

Subject(s)
Self Tolerance/immunology , T-Lymphocytes, Regulatory/cytology , T-Lymphocytes, Regulatory/immunology , Animals , Female , Male
19.
Regulatory T cells: Peripheral positioning.
Leavy, Olive.
Nat Rev Immunol ; 16(1): 2-3, 2016 Jan.
Article in English | MEDLINE | ID: mdl-26655626

Subject(s)
Homeostasis/immunology , T-Lymphocytes, Regulatory/immunology , Animals , Female
20.
Reproductive immunology: Evading immunosurveillance in endometriosis.
Leavy, Olive.
Nat Rev Immunol ; 15(12): 729, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26567919

Subject(s)
Endometriosis/pathology , Estrogen Receptor beta/metabolism , Inflammasomes/metabolism , Menstruation/metabolism , Animals , Female , Humans
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