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2.
Mikrobiologiia ; 55(2): 217-22, 1986.
Article in Russian | MEDLINE | ID: mdl-3523167

ABSTRACT

Two Bacillus mesentericus strains with a high activity of proteolytic enzymes having the thrombolytic action were selected from a group of its collection strains. The effect of different carbon sources on the synthesis of proteases was studied. A growth medium containing potato broth (10%), peptone (0.5%) and lactose (0.5%) allowed one to obtain a cultural broth dissolving human blood clots within 2.5 to 3 hours in experiments in vitro.


Subject(s)
Bacillus/enzymology , Fibrinolytic Agents/metabolism , Peptide Hydrolases/biosynthesis , Caseins/metabolism , Culture Media/metabolism , Fibrinolysis/drug effects , Fibrinolytic Agents/pharmacology , Humans , Peptide Hydrolases/pharmacology , Time Factors
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