ABSTRACT
We report here a case of a primitive angiosarcoma of the bone occurring in Paget's disease. Only one case has been previously described in the literature. We review other types of tumours occurring in Pagetic bone and discuss medical and surgical management.
Subject(s)
Bone Neoplasms , Hemangiosarcoma , Ilium , Osteitis Deformans , Bone Neoplasms/diagnosis , Bone Neoplasms/etiology , Bone Neoplasms/therapy , Hemangiosarcoma/diagnosis , Hemangiosarcoma/etiology , Hemangiosarcoma/therapy , Humans , Ilium/diagnostic imaging , Ilium/pathology , Male , Middle Aged , Osteitis Deformans/complications , Tomography, X-Ray ComputedABSTRACT
A case of Schistosoma hematobium epididymal bilharzia is reported. This case is remarkable on the one hand because of the extreme longevity of the trematodes (30 years), illustrated by the presence of viable eggs in the epididymis, and secondly by the isolated epididymal localization of the parasite.
Subject(s)
Epididymis , Schistosomiasis haematobia/parasitology , Animals , Humans , Male , Middle Aged , Schistosoma haematobium/physiology , Testicular Diseases/parasitology , Time FactorsSubject(s)
Douglas' Pouch/cytology , Polycystic Ovary Syndrome/pathology , Salpingitis/pathology , Adult , Female , Humans , Vaginal SmearsABSTRACT
The pathology of six cases of alpha-chain disease (alpha-CD), four of which were followed until complete remission or death, was studied by histologic, immunofluorescence and ultrastructural techniques. The lesions could be classified in three histopographical stages. The late stage C is an immunoblastic sarcoma probably deriving from the same clone as the initial plasmacytic stage A, stage B being a transitional one between A and C. The asynchronism of the lesions in different organs in the same patient requires a laparotomy for an accurate staging which determines the prognosis and the treatment. Complete and prolonged remissions have been observed at stage A only, sometimes with oral antibiotic treatment alone. At all stages, alpha-CD and the "Mediterranean lymphoma" share identical aetiological, clinical and pathological features. Accurate immunological studies will determine the precise-frequency of alpha-CD protein synthesis in the latter syndrome.
Subject(s)
Heavy Chain Disease/pathology , Immunoglobulin Heavy Chains , Immunoglobulin alpha-Chains , Adult , Anti-Bacterial Agents/therapeutic use , Bone Marrow/pathology , Clone Cells/pathology , Diagnosis, Differential , Female , Heavy Chain Disease/blood , Heavy Chain Disease/etiology , Heavy Chain Disease/immunology , Heavy Chain Disease/therapy , Humans , Intestinal Mucosa/pathology , Intestinal Neoplasms/pathology , Intestine, Small/pathology , Liver/pathology , Lymph Nodes/pathology , Lymphoma/pathology , Male , Mesentery , Middle Aged , Plasma Cells/pathology , Prognosis , Rectum/pathology , Spleen/pathology , Stomach/pathologySubject(s)
Adenocarcinoma/diagnosis , Therapeutic Irrigation , Uterine Neoplasms/diagnosis , Biopsy, Needle , Cytodiagnosis , Female , Humans , Uterus/pathologySubject(s)
Breast Neoplasms/pathology , Breast/pathology , Lymphoma, Non-Hodgkin/pathology , Adult , Female , HumansABSTRACT
In scleroderma, the scapular striated muscles may be affected showing rapid fatigability, and sometimes, muscle wasting with EMG changes. The smooth muscle changes, well known in the esophagus, where they lead to loss of peristalsis, may also be marked in other parts of the digestive tract. They lead to various symptoms, such as cramps, vomiting and diarrhea.