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1.
Breast Cancer Res Treat ; 100(3): 247-54, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17033929

ABSTRACT

PURPOSE: The purpose of this prospective study was to test computed tomography (CT) in the evaluation of local breast cancer recurrence. MATERIALS AND METHODS: Our study population included 103 women referred for mamma CT examination for reasons of suspicious findings in a conservatively treated breast. In these patients, both clinical and conventional imaging studies (mammography, ultrasonography) features of local recurrences were non specific or suspicious. The patients underwent breast CT before and 90 s after intra-venous contrast medium administration. Criterion for cancer recurrence was detection of a lesion with an enhancement of 20 UH or more. The final diagnosis was based on operative histopathological findings or follow-up for over two years. RESULTS: Local recurrence was confirmed on histology in 52 patients. CT identified 47 breast recurrent cancers. False-positive contrast enhancement was seen in five patients. CT showed 90% sensitivity, 90% specificity and 90% accuracy. CONCLUSION: Although mamma CT examination proved to have a high diagnostic efficacy in evaluating breast cancer recurrence, routine computed tomography is unnecessary for most patients.


Subject(s)
Breast Neoplasms/diagnostic imaging , Contrast Media , Mammography/methods , Tomography, Spiral Computed , Ultrasonography, Mammary , Adult , Aged , Aged, 80 and over , Breast Neoplasms/therapy , Female , Follow-Up Studies , France , Humans , Middle Aged , Predictive Value of Tests , Prospective Studies , Recurrence , Sensitivity and Specificity , Time Factors , Treatment Outcome
2.
J Radiol ; 81(3): 243-5, 2000 Mar.
Article in French | MEDLINE | ID: mdl-10740075

ABSTRACT

Osteosarcoma is a malignant bone tumour of mesenchymal osteoid tissue origin. Osteosarcoma can be primitive, but it may also complicated a Paget's disease of bone. We described a 75yearold man with a right thigh mass discovered after a motoring accident. Histopathologic examination revealed the diagnosis of osteosarcoma. Plain film Xrays showed Paget's lesion of the right pelvis bone. CT and MRI allowed complete evaluation of this lesion. Final diagnosis was those of malignant transformation of Paget disease. The patient was refused for surgery in view of the size of the tumour and chimiotherapy followed.


Subject(s)
Bone Neoplasms/diagnosis , Bone Neoplasms/etiology , Osteitis Deformans/complications , Osteosarcoma/diagnosis , Osteosarcoma/etiology , Pelvic Bones , Aged , Aged, 80 and over , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Biopsy , Bone Neoplasms/drug therapy , Humans , Magnetic Resonance Imaging , Male , Osteosarcoma/drug therapy , Prognosis , Tomography, X-Ray Computed
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