1.
Acta Crystallogr C
; 57(Pt 4): 487-8, 2001 Apr.
Article
in English
| MEDLINE
| ID: mdl-11313603
ABSTRACT
The small synthetic peptide, benzyl 2-(tert-butoxycarbonyl-amino)isobutyrate, C(16)H(23)NO(4), has the alpha-helical conformation [/varphi/ = 55.8 (2) degrees and /psi/ = 37.9 (2) degrees] observed in peptide fragments of peptaibols containing the alpha-aminoisobutyric acid (Aib) residue. The structure shows no intramolecular hydrogen bonding, which would disrupt the limited conformational freedom associated with this amino acid. Two weak intermolecular hydrogen contacts are observed.