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1.
Comput Biol Med ; 178: 108634, 2024 Jun 08.
Article in English | MEDLINE | ID: mdl-38917531

ABSTRACT

Nasal airflow obstruction correlates with several ailments, such as higher patency, increased friction at the mucosal wall or the so-called Little's area, improper air conditioning, and snoring. Nasal dilators are frequently employed, mainly due to their ease of access and use, combined with their non-permanent and non-surgical nature. Their overall efficacy, however, has not been clearly demonstrated so far, with some studies reporting conflicting outcomes, mainly because being based on subjective evaluations. This study employs Computational Fluid Dynamics simulations to analyze the flow inside a real nose, performs an objective assessment of a nasal dilator's effect in terms of airflow and air conditioning, reporting flow paths, friction levels, heat and water fluxes and detailed temperature and humidity distributions. Coincidentally, the studied nose presents a septal deviation, with one nostril being wider than the other. The tubes of the dilator used in both nostrils are identical, as with any standard commercial dilator. Consequently, the dilator widens one nostril, as intended, but results in an obstruction in the other. This allows simultaneously addressing two situations, the nominal function of the dilator, as well as an off-design case. Results indicate a 24 % increase in nasal patency in the design situation. The effect, however, is limited, as quantified by appropriate measures, such as the flow-generated friction at the nose surfaces and the temperature fluxes. Hence, the effect of such a dilator in nominal conditions is perhaps not as large as might be hoped. In the off-design situation, nasal resistance increases by 62 %, an undesirable effect, illustrating the consequences of using an inappropriate dilator.

2.
Comput Biol Med ; 77: 214-21, 2016 10 01.
Article in English | MEDLINE | ID: mdl-27598464

ABSTRACT

The surgical term "turbinectomy" encompasses many variations in the location and extent of removal. As a systemic approach to consider the negative impact of middle turbinectomy(MT), such as the excessive removal of turbinate, airflows inside a pre-surgery model and a series of virtual surgery models were numerically analyzed and compared. These models simulate three variations of partial MT(three bilateral and three unilateral) with varying resection volume and location. Each middle turbinectomy results in alterations of flow and thermal parameters, such as nasal resistance (NR), velocity, temperature, wall shear stress(WSS) and wall heat transfer(WHT). WSS distributions were also considered in connection with mucosal secretion. The tendency of changes in nasal functions and airflow characteristics was identified with respect to resection volume and location. A counter-rotating vortical structure was seen in the region of widened middle airway for the case of total resection of middle turbinate. Maximum velocity and WSS near sphenopalatine ganglion, which was a possible explanation for headache after total resection of middle turbinate, was increased. Changes in NR and WHT for bi-lateral resection cases were greater than those for unilateral resection cases. While the physiological changes in four partial MT models were insignificant, changes in near total resection model was prominent. Although our surgical simulation was done for a single case, we postulate that the removal of the anterior inferior part of middle turbinate while preserving posterior margin will not alter airflow characteristics extensively. These findings will help designing surgical plans for partial MT.


Subject(s)
Computer Simulation , Hydrodynamics , Models, Anatomic , Turbinates , Airway Resistance , Body Temperature , Humans , Imaging, Three-Dimensional , Nasal Cavity/physiopathology , Nasal Mucosa/physiopathology , Turbinates/diagnostic imaging , Turbinates/physiopathology , Turbinates/surgery
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