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BMJ Case Rep ; 20142014 Feb 20.
Article in English | MEDLINE | ID: mdl-24557479

ABSTRACT

A 42-year-old man who was being treated for pneumonia developed severe, sudden-onset abdominal pain with features of shock and peritonism. The clinical picture combined with radiological investigations raised suspicion of a bowel perforation necessitating urgent surgical review and emergency laparotomy. This diagnosed a jejunal perforation with abnormal lymph nodes. Histological examination confirmed diffuse large B-cell lymphoma. The patient was subsequently started on a course of chemotherapy. While gastrointestinal perforation secondary to antilymphoma treatment is a well-recognised complication, primary perforation caused by the lymphoma itself must always be considered.


Subject(s)
Intestinal Perforation/etiology , Jejunal Diseases/etiology , Lymphoma, B-Cell/complications , Lymphoma, B-Cell/diagnosis , Rare Diseases/etiology , Adult , Antibodies, Monoclonal, Murine-Derived/therapeutic use , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Cyclophosphamide/therapeutic use , Doxorubicin/therapeutic use , Humans , Intestinal Perforation/surgery , Jejunal Diseases/surgery , Lymphoma, B-Cell/drug therapy , Male , Prednisone/therapeutic use , Rare Diseases/surgery , Rituximab , Vincristine/therapeutic use
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