ABSTRACT
Central nervous system (CNS) infection with Morganella morganii is very rare. We describe a 38-year-old female patient with frontal brain abscess caused by M morganii who was unsuccessfully treated. We also review all reported cases of Morganella CNS infections with an emphasis on treatment modalities and outcomes. Aggressive surgical management and appropriate antimicrobial therapy can lead to cure, but the mortality rate for these infections remains high.
Subject(s)
Central Nervous System Infections/diagnosis , Enterobacteriaceae Infections/diagnosis , Morganella morganii/pathogenicity , Adult , Aged , Anti-Bacterial Agents/classification , Anti-Bacterial Agents/therapeutic use , Central Nervous System Infections/diagnostic imaging , Central Nervous System Infections/drug therapy , Central Nervous System Infections/microbiology , Enterobacteriaceae Infections/diagnostic imaging , Enterobacteriaceae Infections/drug therapy , Enterobacteriaceae Infections/microbiology , Fatal Outcome , Female , Humans , Magnetic Resonance Imaging , Male , Microbial Sensitivity Tests , Middle Aged , Morganella morganii/drug effects , Tomography, X-Ray ComputedABSTRACT
Corynebacterium striatum (CS) is an underappreciated human pathogen that has been associated with serious infections in both immunocompetent and immunocompromised hosts. CS infections tend to be more frequent in males and major infection sites have included blood stream, lung, and central nervous system. Most are nosocomially acquired and there is a significant association with medical devices ranging from intravascular catheters to central nervous system drainage devices. Empiric therapy with vancomycin is advisable as susceptibility to other agents is variable. Treatment may also include removal of foreign material such as an intravascular catheter. The present review describes the wide spectrum of infections associated with CS and we add a unique case of CS pancreatic abscess where treatment included linezolid.
