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1.
J Nanosci Nanotechnol ; 13(6): 4325-9, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23862495

ABSTRACT

The periodic beveled micro-rods (BMRs) were constructed on the emission surface of GaN-based vertical light-emitting diodes (VLEDs) in order to improve the light-extraction efficiency. It was experimentally demonstrated that the light output power of the VLEDs with a periodic BMR (BMR-VLED) were enhanced about 15.6%, compared with that of the VLEDs with randomly textured surface (RT-VLED) at an injection current of 350 mA. This finding indicates that the photons emitted from the active layer were well out-coupled at an n-GaN surface having a periodic BMR structure, resulting in an increase in the probability of escaping from the VLED structure.

2.
J Nanosci Nanotechnol ; 11(10): 8695-9, 2011 Oct.
Article in English | MEDLINE | ID: mdl-22400245

ABSTRACT

The enhancement of light extraction efficiency is observed when the hole-shape patterned ITO ohmic contact layer and AgIn reflector is adopted in GaN-based flip-chip (FC) light emitting diodes (LEDs). ITO layer (140 nm) and AgIn (200 nm) was deposited on the top of p-GaN by in-line DC sputtering and electron beam evaporating system, respectively. The ITO ohmic contact layer showed a low specific contact resistance of 2.66 x 10(-5) Omega cm(-2) and high transmittance of >85% at visible spectral regions. The AgIn reflector exhibited a low specific contact resistance of 1.90 x 10(-5) Omega cm(-2) and high reflectance of approximately 84% at visible spectral regions. Comparing with unpatterned ITO/AgIn layer, the optical output power of GaN-based FC LEDs improves approximately 30% by the adoption of micro size hole-shape patterned ITO ohmic contact layer and AgIn reflector.

3.
Planta Med ; 68(11): 971-4, 2002 Nov.
Article in English | MEDLINE | ID: mdl-12451485

ABSTRACT

Recent epidemiological studies have demonstrated that ginseng intake is associated with a reduced risk for environmentally related cancers. However, the effects of ginsenosides on the proliferation of renal proximal tubule cells have not yet elucidated. This study investigated the effect of total ginsenosides, protopanaxatriol (PT) saponin, and protopanaxadiol (PD) saponin fraction on epidermal growth factor (EGF)-induced renal cell proliferation and, furthermore, c-fos and c-jun gene expression. In the present study, total ginsenosides (10 -6 g/ml) completely blocked EGF-induced DNA synthesis and cell growth. In contrast, the PT and PD fractions partially blocked it. In addition, the EGF-induced increase of c-fos and c-jun gene expression was completely blocked by total ginsenosides and partially by PT and PD saponins. In conclusion, ginsenosides, in part, inhibit EGF-induced cell proliferation via decrease of c-fos and c-jun gene expression in primary cultured rabbit renal proximal tubular cells (PTCs). Abbreviations. EGF:epidermal growth factor PD:protopanaxadiol PT:protopanaxatriol PTCs:primary cultured renal proximal tubule cells


Subject(s)
Cell Division/drug effects , Ginsenosides/pharmacology , Kidney Tubules, Proximal/cytology , Kidney Tubules, Proximal/drug effects , Panax , Phytotherapy , Sapogenins/pharmacology , Triterpenes/pharmacology , Animals , Dose-Response Relationship, Drug , Epidermal Growth Factor , Gene Expression Regulation, Neoplastic , Genes, fos/genetics , Genes, jun/genetics , Ginsenosides/administration & dosage , Ginsenosides/therapeutic use , Humans , Kidney Neoplasms/prevention & control , Male , Plant Roots , Rabbits , Sapogenins/administration & dosage , Sapogenins/therapeutic use , Thymidine/metabolism , Triterpenes/administration & dosage , Triterpenes/therapeutic use
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