Octodon degus (Molina 1782): a model in comparative biology and biomedicine.

One major goal of integrative and comparative biology is to understand and explain the interaction between the performance and behavior of animals in their natural environment. The Caviomorph, Octodon degu, is a native rodent species from Chile, and represents a unique model to study physiological and behavioral traits, including cognitive and sensory abilities. Degus live in colonies and have a well-structured social organization, with a mostly diurnal-crepuscular circadian activity pattern. More notable is the fact that in captivity, they reproduce and live between 5 and 7 yr and show hallmarks of neurodegenerative diseases (including Alzheimer's disease), diabetes, and cancer.

Husbandry and breeding in the Octodon degu (Molina 1782).

The Octodon degu is a native rodent species from South America, which lives in colonies with a well-structured social organization grouping of 5-10 young and 2-5 adult animals sharing a burrow system. They show a temperature-dependent diurnal-crepuscular activity pattern. In nature they rarely survive 2 yr, mostly because of predation. However, in captivity, females reproduce for 4-4.5 yr, and both sexes live for 5-7 yr. Males remain fertile until death. Some care is required to maintain healthy degus, particularly breeding females. Here we describe husbandry and breeding guidelines from the experience of the University of Michigan degu colony. With the husbandry practices described here, 90% of pups born in our colony reach maturity (6 mo of age), and no diarrheal diseases are apparent in our adult population.