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1.
Selective recognition of pyrophosphate in water using a backbone modified cyclic peptide receptor.
McDonough, Matthew J; Reynolds, Aaron J; Lee, Wee Yu Gladys; Jolliffe, Katrina A.
Chem Commun (Camb) ; (28): 2971-3, 2006 Jul 28.
Article in English | MEDLINE | ID: mdl-16832507

ABSTRACT

A cyclic peptide based receptor, bearing two dipicolylamino arms complexed to zinc(II) ions, binds pyrophosphate ions with high affinity and selectivity in aqueous solution as determined using an indicator displacement assay.


Subject(s)
Diphosphates/chemistry , Peptides, Cyclic/chemistry , Receptors, Peptide/chemistry , Water/chemistry , Diphosphates/metabolism , Models, Molecular , Peptides, Cyclic/metabolism , Receptors, Peptide/metabolism , Water/metabolism , Zinc/chemistry , Zinc/metabolism
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