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1.
J Craniofac Surg ; 2024 Jan 17.
Article in English | MEDLINE | ID: mdl-38231264

ABSTRACT

The zygomaticomaxillary complex and the orbital floor are commonly affected by mid-face fractures; their fractures pose challenges in reconstruction and can result in complications, such as enophthalmos. This study explores an intraoral approach with the help of a customized balloon technique and a contrast agent as an alternative to the conventional methods. A case report of a 67-year-old man with complex midfacial trauma is presented. The surgical process involved open reduction through an intraoral approach along with a transantral approach with the customized balloon technique. The procedure aimed to achieve reduction, fixation, and reconstruction of a complex mid-face fracture.

2.
J Korean Assoc Oral Maxillofac Surg ; 49(3): 152-156, 2023 Jun 30.
Article in English | MEDLINE | ID: mdl-37394935

ABSTRACT

Plexiform neurofibroma is a rare benign tumor and a special subtype of neurofibromatosis 1. This report is a literature review with a case of patient with facial hemorrhage observed at the site of neurofibroma removal in the right lower face due to minor trauma. Through PubMed search, using terms ((facial hematoma) OR (facial bleeding)) AND (neurofibromatosis), 86 articles were identified, and five related articles (six patients) were finally selected. Of the six patients, two had previously undergone embolization. However, as a result, all patients received open surgery to remove hematomas. The hemostatic methods mentioned were vascular ligation (five patients), hypotensive anesthesia (two patients), and postoperative blood transfusion (four patients). In conclusion, spontaneous or minimally traumatic bleeding is possible in neurofibromatosis patients. In most cases, it can be resolved by vascular ligation under hypotensive anesthesia. Optionally, prior embolization and supplementary tissue adhesive may be used.

3.
J Korean Assoc Oral Maxillofac Surg ; 49(2): 100-104, 2023 Apr 30.
Article in English | MEDLINE | ID: mdl-37114449

ABSTRACT

Autogenous bone grafts from the mandibular ramus are a known source of inadequate bone volume scenarios of the residual alveolar ridge. However, the conventional block-type harvesting technique cannot prevent bone marrow invasion, which can cause postoperative complications such as pain, swelling, and inferior alveolar nerve injury. This study aims to suggest a complication-free harvesting technique and present the results of bone grafting and donor sites. One patient received two dental implants with a complication-free harvesting technique that involves creation of ditching holes with a 1 mm round bur. Sagittal, coronal, and axial osteotomies produced grid-type cortical squares using a micro-saw and a round bur to confirm the cortical thickness. The grid-type cortical bone was harvested from the occlusal aspect, and the harvesting was extended through an additional osteotomy on the exposed and remaining cortical bone to prevent bone marrow invasion. The patient did not suffer postoperative severe pain, swelling, or numbness. After 15 months, the harvested site exhibited new cortical bone lining, and the grafted area had healed to a cortico-cancellous complex with functional loading of the implants. Our technique, grid-type cortical bone harvesting without bone marrow invasion, allowed application of autogenous bone without bone marrow invasion to achieve acceptable bone healing of the dental implants and to regenerate the harvested cortical bone.

4.
J Korean Assoc Oral Maxillofac Surg ; 48(3): 182-187, 2022 Jun 30.
Article in English | MEDLINE | ID: mdl-35770361

ABSTRACT

Superolateral dislocation of the condyle is a rare mandibular fracture. The treatment goal is to return the dislocated condyle to its original position to recover normal function. This study reports on superolateral dislocation of the condyle with mandibular body fracture. The mandibular body was completely separated, and the medial pole of the condyle head was fractured. The condyle segment was unstable and easily dislocated after reduction. The temporalis muscle on the condyle segment might have affected the dislocation of the condyle. A coronoidectomy was performed to disrupt the function of the temporalis muscle on the condyle segment in order to successfully reduce the dislocated condyle. Coronoidectomy is a simple procedure with minimal complications. We successfully performed a coronoidectomy to reduce the superolateral displaced condyle to its original position to achieve normal function. Coronoidectomy can be effectively used for reduction of superolaterally displaced condyles combined with severe maxilla-mandibular fractures.

5.
J Funct Biomater ; 14(1)2022 Dec 20.
Article in English | MEDLINE | ID: mdl-36662051

ABSTRACT

The purpose of this retrospective study was to evaluate bone healing after autogenous demineralized dentin matrix (DDM) grafts, focusing on the distal root of the mandibular second molar after the extraction of the third. We included retrospective data from 20 patients who had undergone molar extractions (15 male, 41.9 ± 12.0 years) between January 2020 and September 2022 and had DDM grafts implanted on the extraction socket, immediately ("immediate graft") or 6 weeks ("delayed graft") after the first surgery without primary closure. Patients who underwent grafting on only one side were used as the control group (n = 4). Bone defects at the mandibular second molar were measured preoperatively and 4 months after the graft surgery using cone-beam computed tomography (CBCT). Improvement of bone defect (i.e., the change in the bony defect pre- vs. postoperatively) was compared between the control and graft groups using the Wilcoxon Signed Rank test, and the difference between immediate and delayed grafts was analyzed with the Mann-Whitney U test. Complications such as infections or graft failure did not occur. Although pre-operative defects were smaller in the control than in the graft group (2.98 ± 1.77 and 10.02 ± 3.22 mm, p = 0.001), post-operative defects were similar in both (2.12 ± 0.59 and 2.29 ± 1.67 mm, respectively). The improvement ratio was not statistically significant in the control group (22.68 ± 15.36%) but a difference was observed in the graft group (76.70 ± 15.36%, p = 0.001). The amount of improvement of bone defect was not affected by graft timing or patient sex. In conclusion, DDM can improve bone defect at the distal aspect of the mandibular second molar after third molar extraction.

6.
J Korean Assoc Oral Maxillofac Surg ; 47(2): 135-140, 2021 Apr 30.
Article in English | MEDLINE | ID: mdl-33911046

ABSTRACT

Since the first report of a nasal septal abscess (NSA) from a dental origin (1920), six articles have been published in the English literature to date. The most common cause of NSA is an infection of the nasal septal hematoma after trauma. This is a report of an uncommon cause of NSA with a dental origin. A PubMed search performed regardless of year and country using the terms ("nasal septal abscess") OR ("nasal septum abscess") initially yielded 229 articles. After screening, seven articles (eight patients) were selected. Addition of two related articles produced a total of nine articles (10 patients) to be included. The age of the included patients ranged from 7 to 69 years (mean, 32.82 years; standard deviation, ±23.86 years). The sex composition was as followed: males (n=7; 63.6%), females (n=4; 36.4%). Dental histories were various: periapical lesions, caries, extraction, endodontic therapy, and cystic lesions. The maxillary incisor dominated as the tooth of origin. Early diagnosis and treatment of NSAs are important to avoid not only facial deformity, but also severe complications (e.g., intracranial infection). If NSA is suspected in patients without facial trauma, the possibility of a dental origin, especially from the maxillary incisor area, should be considered.

7.
J Korean Assoc Oral Maxillofac Surg ; 47(1): 40-46, 2021 Feb 28.
Article in English | MEDLINE | ID: mdl-33632976

ABSTRACT

Marsupialization is widely used as a primary treatment modality for reducing size of large cysts. However, there is no recommendation for specific duration of marsupialization. In addition, Carnoy's solution usually is applied at the time of enucleation as a fixative agent. In this report, we present an appropriate marsupialization duration of ameloblastoma involving two unerupted teeth. In this present study, marsupialization using a Foley catheter was performed in two cases of ameloblastoma of the mandible involving two adjacent impacted teeth. Carnoy's solution was applied for 3-5 minutes after enucleation in both patients. Periodically during marsupialization, the size of the radiolucency was measured in panoramic view, and clinical examination was performed. No remarkable paresthesia or soft tissue injury was observed after application of Carnoy's solution or during follow-up. We recommend 12 to 16 weeks as an adequate marsupialization duration for a large ameloblastoma involving two impacted teeth based on increased radiopacity along the margins of the lesions. Poor oral hygiene was an issue after 12 weeks of marsupialization in one case. There were no remarkable complications with Carnoy's solution in either case. The Foley tube has a two-way system that is more effective for irrigating the cavity than is the conventional one-way system.

8.
Maxillofac Plast Reconstr Surg ; 43(1): 4, 2021 Jan 19.
Article in English | MEDLINE | ID: mdl-33469729

ABSTRACT

PURPOSE: Several investigations have been performed for a postoperative edema after extraction, but the results have been controversial due to low objectivity or poorly reproducible assessments of the edema. The aim of this study was to suggest a classification and patterns of postoperative edema according to the anatomical division associated with extraction of mandibular third molar as a qualitative evaluation method. METHODS: This study was conducted forty-four mandibular third molars extracted and MRI was taken within 48 h after extraction. The postoperative edema space was classified by MRI (one anatomic component-buccinator muscle-and four fascial spaces-supra-periosteum space, buccal space, parapharyngeal space, and lingual space), and evaluated independently by two examiners. The inter-examiner reliability was calculated using Kappa statistics. RESULTS: The evaluation of buccinator muscle edema showed good agreement and the fascial spaces showed constant high agreement. The incidence of postoperative edema was high in the following order: supra-periosteum space (75.00%), buccinator muscle (68.18%), parapharyngeal space (54.55%), buccal space (40.91%), and lingual space (25.00%). CONCLUSION: Postoperative edema could be assessed clearly by each space, which showed a different tendency between the anatomic and fascial spaces.

9.
J Craniofac Surg ; 32(4): 1540-1544, 2021 Jun 01.
Article in English | MEDLINE | ID: mdl-33229994

ABSTRACT

ABSTRACT: The purpose of this article is to introduce simple, minimally invasive, more effective, and more comfortable method using a customized balloon with contrast agent for orbital floor fracture. The customized balloon was fabricated to compensate for its shortcomings, based on the experiences from four patients who underwent the surgery of orbital floor fracture using a Foley catheter.In a 33-year-old female patient with only orbital floor fracture, the reduction was performed using a transmaxillary approach with a customized balloon. The customized balloon was made using latex glove and 6 French gavage tube, and the contrast agent was injected within the balloon. A micro saw was used to form a window on the anterior wall of the maxillary sinus. Compared to the round bur, a micro saw can create an internal bevel along with minimal bone removal, which makes it possible to insert the bone fragment tightly without falling into the maxillary sinus when the fragment is repositioned. The use of contrast agent makes it more visible to determine the position of the balloon instantly during surgery by take portable radiograph. The balloon has removed after 3 weeks and no diplopia or no enophthalmos was observed. There remained very small defect on the anterior sinus wall about the size of gavage tube.The transmaxillary approach, along with a conjunctival or subciliary approach, can be a good choice for the treatment of orbital fractures. Compared to the conventional Foley catheter, the application of a customized balloon and contrast agent supports the entire orbital floor evenly and wide, and fills the maxillary sinus without an empty space. It is easy to check the location of the balloon through x-ray photography during surgery, and has a very little discomfort for the patient.


Subject(s)
Enophthalmos , Orbital Fractures , Adult , Contrast Media , Female , Humans , Maxillary Sinus , Orbital Fractures/diagnostic imaging , Orbital Fractures/surgery , Tomography, X-Ray Computed
10.
J Korean Assoc Oral Maxillofac Surg ; 46(6): 417-421, 2020 Dec 31.
Article in English | MEDLINE | ID: mdl-33377467

ABSTRACT

OBJECTIVES: The purpose of this paper is to introduce an effective technique to easily obtain adequate amounts of keratinized gingiva and vestibular depth. MATERIALS AND METHODS: Free gingiva (vertical height 10 mm) was harvested on the palatal mucosa and a partial thickness flap was elevated on the recipient site with same width as the free gingiva graft. After a conventional suture, a titanium mesh covered the graft and was fixed with miniscrews. Titanium mesh was removed 4.1±2.5 weeks after surgery. The amount of keratinized gingiva and vestibular depth was measured at the final follow-up. RESULTS: Nine patients (males 4, females 5; 53.9±14.1 years) who underwent bone graft surgery before vestibuloplasty were included. No free gingival graft failure or complications were encountered in any of the patients. The relapse rate for vestibular depth (23.3%) was lower than that for keratinized gingiva (48.3%) after 34.4±14.4 months (P=0.010). CONCLUSION: Vestibuloplasty with a free gingival graft using titanium mesh could be achieved with an acceptable amount of keratinized gingiva and an appropriate vestibular depth around dental implant.

11.
Maxillofac Plast Reconstr Surg ; 42(1): 31, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32995343

ABSTRACT

BACKGROUND: Fibrous dysplasia (FD) is a rare, sporadic, and benign congenital condition in which normal cancellous bone is replaced by fibro-osseous tissue with immature osteogenesis. FD localized in the cranial and facial bones is called craniofacial fibrous dysplasia (CFD). Cystic degeneration in CFD cases is rare; cystic degeneration appearing in both the maxilla and the mandible FD lesion is even rarer. The aim of this article was to report a case of fibrous dysplasia of the mandible and maxilla complicated by nonspecific cystic degeneration. CASE PRESENTATION: A 30-year-old woman presented with a rare case of non-specific cystic degeneration in a mandible and maxilla FD lesion that occurred 11 years after surgery. She was diagnosed with polyostotic CFD and underwent maxillary and mandibular bone contouring. Cyst enucleation under general anesthesia was performed in the mandibular region due to pain and discomfort. CONCLUSIONS: In cases involving non-aggressive and non-invasive FD cystic degeneration in focal areas, conservative treatment is recommended. However, if cystic degeneration of FD develops rapidly and causes discomfort, pain, or dysfunction, surgical treatment should be considered.

12.
Maxillofac Plast Reconstr Surg ; 42(1): 16, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32509707

ABSTRACT

BACKGROUND: Cyst enucleation, which extracts only the tumor with the application of Carnoy's solution (CS), has been suggested as a conservative treatment with a low recurrence rate and morbidity. However, there has been a concern that CS's contact with inferior alveolar nerve (IAN) can cause neurons to degenerate and cause sensory dysfunction. The purpose of this retrospective cohort study aimed to investigate the neurosensory function after surgical treatment with or without the application of CS. METHODS: While controlling the effects of sex, age, follow-up period, and invasion size of the tumor, we performed the binary logistic regression analysis to examine whether or not the sensory function of the patients who were treated with CS (n = 19) for the cyst enucleation procedure was significantly different from those who were not treated with CS (n = 58) at the end of the follow-up period. RESULTS: The logistic regression result showed that the use of CS was not significantly related to the normalness of sensory function at the end of the follow-up period. Rather, the invasion size of the cyst was significantly associated with sensory dysfunction. CONCLUSIONS: CS may be used for patients who are diagnosed with OKC and UAM without much fear of its impact on sensory dysfunction. However, a small number of patients who were treated with CS experienced severe sensory damage and did not recover at the end of the follow-up period, suggesting the need for further analysis of these patients.

13.
Tissue Eng Part B Rev ; 26(3): 284-293, 2020 06.
Article in English | MEDLINE | ID: mdl-31928139

ABSTRACT

In 2007, recombinant human bone morphogenetic protein-2 (rhBMP-2) was approved for use in humans at a concentration of 1.5 mg/mL with absorbable collagen sponges as an alternative to autogenous bone grafts for alveolar ridge augmentation, defects associated with extraction sockets, and sinus augmentation. However, the use of supraphysiological doses and the insufficient retention of rhBMP-2, when delivered through collagen sponge, result in dose-dependent side effects related to off-label use. Demineralized dentin matrix (DDM), an osteoinducing bone substrate, has been used as an rhBMP-2 carrier since 1998. In addition, DDM has both microparticle and nanoparticle structures, which do not undergo remodeling, unlike bone. In vitro, DDM is a suitable carrier for BMP-2, with the continued release over 30 days at concentrations sufficient to stimulate osteogenic differentiation. In this review, we discuss the histological outcomes of DDM loaded with rhBMP-2 to highlight the biological functions of exogenous rhBMP-2 associated with the DDM carrier in clinical applications in implant dentistry. Impact Statement Demineralized dentin matrix (DDM) has been used as an recombinant human bone morphogenetic protein (rhBMP-2) carrier and osteo-inducing bone substrate to facilitate continued release and stimulate osteogenic differentiation. In this review, we discuss the histological outcomes of DDM loaded with rhBMP-2 in order to highlight the biological functions of exogenous rhBMP-2 associated with the DDM carrier in clinical applications in implant dentistry.


Subject(s)
Bone Morphogenetic Protein 2/pharmacology , Dentin/cytology , Transforming Growth Factor beta/pharmacology , Alveolar Process/cytology , Animals , Humans , Prostheses and Implants , Recombinant Proteins/pharmacology
14.
Maxillofac Plast Reconstr Surg ; 41(1): 19, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31106163

ABSTRACT

BACKGROUND: The submucous cleft palate (SMCP) is a type of cleft palate that may result in velopharyngeal insufficiency (VPI). Palate muscles completely separate oral and nasal cavities by closing off the velopharynx during functional processes such as speech or swallow. Also, hypernasality may arise from anatomical or neurological abnormalities in these functions. Treatments of this issue involve a combination of surgical intervention, speech aid, and speech therapy. This case report demonstrates successfully treated VPI resulted from SMCP without any surgical intervention but solely with speech aid appliance and speech therapy. CASE PRESENTATION: A 13-year-old female patient with a speech disorder from velopharyngeal insufficiency that was caused by a submucous cleft palate visited to our OMFS clinic. In the intraoral examination, the patient had a short soft palate and bifid uvula. And the muscles in the palate did not contract properly during oral speech. She had no surgical history such as primary palatoplasty or pharyngoplasty except for tonsillectomy. And there were no other medical histories. Objective speech assessment using nasometer was performed. We diagnosed that the patient had a SMCP. The patient has shown a decrease in speech intelligibility, which resulted from hypernasality. We decided to treat the patient with speech aid (palatal lift) along with speech therapy. During the 7-month treatment, hypernasality measured by a nasometer decreased and speech intelligibility became normal. CONCLUSIONS: Surgery remains the first treatment option for patients with velopharyngeal insufficiencies from submucous cleft palates. However, there were few reports about objective speech evaluation pre- or post-operation. Moreover, there has been no report of non-surgical treatment in the recent studies. From this perspective, this report of objective improvement of speech intelligibility of VPI patient with SMCP by non-surgical treatment has a significant meaning. Speech aid can be considered as one of treatment options for management of SMCP.

15.
J Korean Assoc Oral Maxillofac Surg ; 45(6): 369-373, 2019 Dec.
Article in English | MEDLINE | ID: mdl-31966983

ABSTRACT

This paper describes a patient with an insufficient vestibular depth for a removable partial denture who underwent vestibuloplasty with a free gingival graft using a titanium mesh in the anterior mandible. Free gingiva was harvested from the palatal mucosa, and a partial thickness flap was elevated at the recipient site. After minimal suturing for the graft, a titanium mesh was fixed over the graft. The mesh was removed four weeks after surgery. The patient obtained an adequate vestibular depth and keratinized gingiva eight weeks after surgery without any complications. In this case, an appropriate vestibular depth and keratinized gingiva were easily obtained by vestibuloplasty using a titanium mesh.

16.
Maxillofac Plast Reconstr Surg ; 40(1): 31, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30397593

ABSTRACT

BACKGROUND: Verrucous carcinoma (VC) accounts for 1-10% of cases of squamous cell carcinoma (SCC) in the oral cavity, and 75% of VC occur in the oral cavity. Only 3% of primary intraosseous squamous cell carcinomas (PIOSCC), which means SCC occurring primarily in the bone, are VC. Verrucous carcinoma arising from odontogenic cysts (OC) is very rare, with only seven cases reported to date. CASE PRESENTATION: This study reported a case of a patient who underwent partial maxillectomy and neck dissection for VC that occurred in the right anterior maxilla. The patient was admitted to the emergency department at our institution 8 years ago and showed cystic lesions in the anterior maxilla on facial computed tomography (CT) images. Treatment through other departments including assessment of laceration in the mental region and only suture was performed. This report highlights a very rare case of VC in the right anterior maxilla arising from a previous cystic lesion. CONCLUSIONS: Since PIOSCC can arise from OC, appropriate treatment of intraosseous cysts and regular radiologic evaluation are necesssary. Surgical exicision of the primary lesion without neck dissection can lead to good prognosis for patients with primary intraosseous verrucous carcinoma.

17.
Clin Case Rep ; 5(2): 108-118, 2017 Feb.
Article in English | MEDLINE | ID: mdl-28174633

ABSTRACT

Demineralized dentin matrix block (ABTB: Autogenous Tooth Bone Graft Block) is 3-D scaffold with same components and geometry with alveolar bone. ABTB is well incorporated and remodelled into cortico-cancellous bone with dental implant. The shape and volume were maintained with little marginal bone loss after average 44 months of follow-up.

18.
Maxillofac Plast Reconstr Surg ; 38(1): 44, 2016 Dec.
Article in English | MEDLINE | ID: mdl-27995117

ABSTRACT

BACKGROUND: Hemangioma and vascular malformation are benign vascular lesions that often occur in cephalic and cervical region. Currently, surgical resection, laser therapy, angiographic embolization, use of steroids, and sclerotherapy are used as treatments. CASE PRESENTATION: This study reports three cases of benign vascular lesions that are remarkably treated by sodium tetradecyl sulfate (STS) injection, of which occurred in oral cavity and around the mouth. Three percent of STS was diluted with 0.9 % of normal saline, and it was injected to the lesion site at least once. The result of treatment was evaluated based on clinical findings. CONCLUSION: Surgical treatment of hemangioma and vascular malformation occurred in oral cavity is not normally used because of esthetic issues and potential hemorrhage. On the other hand, sclerotherapy using STS is an effective therapy compare to surgical treatment. Despite the number of STS injection was different for each patient, all three patients had reached satisfactory level through the treatment with gradual diminution of lesions.

19.
Maxillofac Plast Reconstr Surg ; 37(1): 41, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26594640

ABSTRACT

Cleidocranial dysplasia is an autosomal dominant heritable skeletal disorder. The characteristic features of cleidocranial dysplasia (CCD) may include hypoplasia of the clavicle, delayed closure of frontanelles, late tooth eruption, and other skeletal disorders. This case report describes clinical and radiographic manifestations at the age of 11 and 29 of a CCD patient, investigates the mutation of core-binding factor A1 (CBFA1) based on gene analysis, and illustrates successful oral reconstruction with fixed prosthesis and dental implant after the extraction of multiple teeth.

20.
Int J Oral Maxillofac Implants ; 30(5): 1113-8, 2015.
Article in English | MEDLINE | ID: mdl-26394348

ABSTRACT

PURPOSE: The aim of this study was to introduce a novel method of flap advancement without a vertical releasing incision for guided bone regeneration (GBR) and to discuss its clinical outcomes. MATERIALS AND METHODS: This retrospective study involved patients who had received GBR for dental implants between April 2012 and April 2013. In all patients, a typical midcrestal incision was made on the edentulous alveolar ridge, and a sulcular incision was extended to the adjacent two teeth; however, no vertical incision was performed. Instead, a wide periosteal releasing incision and an additional releasing incision that selectively cut part of the facial expression muscles (the orbicularis oris or the buccinator) were used. Postoperative complications, such as swelling, pain, paresthesia, signs of infection, and membrane exposure, were evaluated at 1, 2, 4, 12, and 24 weeks after surgery. RESULTS: Forty sites in 34 patients were evaluated. At all surgical sites, flap advancement of more than 7 mm was attained, and clinically passive primary closure was achieved. All patients experienced slight or mild postoperative swelling without functional limitation or discomfort during mouth opening, eye opening, and swallowing. No long-lasting pain (more than a week), paresthesia, or signs of infection occurred during the follow-up period of 6 months. However, delayed exposure of titanium mesh after 4 months was observed in two patients who had used a provisional removable prosthesis. Within 2 weeks, the exposures closed spontaneously after prosthesis use was halted and careful daily dressing was undertaken. CONCLUSION: The flap advancement technique presented in this study easily enables clinically passive primary closure, and there was no obvious failure of primary closure. This technique could be used successfully in GBR procedures.


Subject(s)
Bone Regeneration/physiology , Guided Tissue Regeneration, Periodontal/methods , Surgical Flaps/surgery , Adolescent , Adult , Aged , Alveolar Bone Loss/surgery , Biocompatible Materials/chemistry , Bone Transplantation/methods , Edema/etiology , Female , Follow-Up Studies , Humans , Male , Membranes, Artificial , Middle Aged , Pain, Postoperative/etiology , Paresthesia/etiology , Periosteum/surgery , Postoperative Complications , Retrospective Studies , Surgical Mesh/adverse effects , Surgical Wound Dehiscence/etiology , Surgical Wound Infection/etiology , Titanium/chemistry , Treatment Outcome , Young Adult
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