1.
Farmaco
; 47(3): 379-85, 1992 Mar.
Article
in English
| MEDLINE
| ID: mdl-1354439
ABSTRACT
Following our research on the arachidonic acid metabolites and their derivatives with potential biological activity, we describe the synthesis of the (+-)-8,12-trans-(5Z, 14Z)-9-oxo-prosta-5,14-dienoic acid, a 11-deoxyprostanoid correlated to the class of Preclavulones, one of the unusual families of marine eicosanoids from the coral Clavularia Viridis with considerable biological interest.
Subject(s)
Eicosanoids/analysis , Prostaglandins, Synthetic/chemical synthesis , Animals , Cnidaria/chemistry , Magnetic Resonance Spectroscopy , Prostaglandins, Synthetic/analysis , Spectrophotometry, Infrared
2.
Farmaco Sci
; 40(4): 249-52, 1985 Apr.
Article
in English
| MEDLINE
| ID: mdl-2990999
ABSTRACT
The convergent synthesis of the iso-Leukotriene B4 (XVI) (as diastereoisomeric mixture with the desired geometry), by Wittig's condensation of the two precursor synthons at 6 (VI) and 14 C (XIV), starting from the common cyclic acrylaldehyde dimer (I), is reported.
Subject(s)
Leukotriene B4/chemical synthesis , Chemical Phenomena , Chemistry , Chromatography, High Pressure Liquid , Stereoisomerism
3.
Minerva Stomatol
; 31(3): 311-26, 1982.
Article
in Italian
| MEDLINE
| ID: mdl-6750348
