[Which species actually exist in relation with time and pH when compounds exhibit several dissociation and kinetic constants: the striking case of a thieno-1,4-diazepine]. / Espèces présentes en solution lorsqu'un composé subit simultanément des phénomènes cinétiques et acido-basiques: cas d'une thièno-1,4-diazépine.

A solution of a molecule having several dissociation and kinetic constants evolves with time and pH-value. Now it is important from a pharmacological standpoint to know which species actually exist in solution. The knowledge of the kinetic and dissociation constants allows to plot the concentrations profiles versus time and versus pH-values of the whole protolytes. This is illustrated with a thieno-1,4-diazepine.