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1.
Cureus ; 16(1): e51808, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38322057

ABSTRACT

Primary sternal cancer is exceptionally rare. Secondary sternal cancer typically arises when cancer spreads either through the bloodstream from other sites or directly from neighboring lung or breast cancers. Pain is the primary symptom, but these metastases can lead to skeletal-related events such as pathological fractures, hypercalcemia, and spinal cord or nerve compression, necessitating surgical or radiotherapy interventions. These events contribute to increased morbidity and costs for both patients and the healthcare system. We report the case of a 63-year-old female patient who presented with a sternal mass and whose further investigations revealed metastatic lung cancer in the sternum.

2.
Cureus ; 15(5): e38778, 2023 May.
Article in English | MEDLINE | ID: mdl-37303384

ABSTRACT

Allergic bronchopulmonary aspergillosis (ABPA) is an underdiagnosed lung condition in patients with asthma and cystic fibrosis. Its clinical and diagnostic manifestations result from an allergic response to multiple antigens expressed by Aspergillus fumigatus, which colonize the bronchial mucus. This report presents the case of a 73-year-old female patient referred to our hospital for uncontrolled asthma for 35 years. The diagnosis of ABPA was made on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum immunoglobulin E, positive aspergillus serology, and bronchiectasis with mucoid impaction. Systemic corticosteroids and antifungal therapy came up with satisfactory clinical results.

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