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J Pharm Biomed Anal ; 70: 245-50, 2012 Nov.
Article in English | MEDLINE | ID: mdl-22846515

ABSTRACT

It has been shown that NMR spectroscopy is an effective analytical method to rapidly screen creams and ointments for counterfeit corticosteroids. Extraction and NMR procedures have been developed. Ten over the counter creams and ointments sold in health care shops were screened and two creams were found to contain counterfeited corticosteroids.


Subject(s)
Adrenal Cortex Hormones/analysis , Counterfeit Drugs/analysis , Fraud , Magnetic Resonance Spectroscopy , Calibration , Chemical Fractionation , Chromatography, Liquid , Magnetic Resonance Spectroscopy/standards , Ointments , Quality Control , Reference Standards , Skin Cream , Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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